Abstract
We present a case of primary plasma cell leukemia with Bence Jones proteinuria. After combination chemotherapy, leukemic cells and the urinary levels Bence Jones protein were decreased. Small lytic bone lesions were detected only in the skull. Typical plasma cells were rarely seen in peripheral blood on the hyperleukocytic phase, however they were increased in the advanced stages. The most important diagnostic sign was persistent expression of CD38 antigen on leukemic cells throughout the entire course of the illness and these leukemic cells expressed very late antigen-4 (VLA-4) but not VLA-5.
| Original language | English |
|---|---|
| Pages (from-to) | 565-568 |
| Number of pages | 4 |
| Journal | Internal medicine (Tokyo, Japan) |
| Volume | 32 |
| Issue number | 7 |
| Publication status | Published - 1993 Jul |
| Externally published | Yes |
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ASJC Scopus subject areas
- Internal Medicine
Cite this
Integrin VLA-5 negative primary plasma cell leukemia. / Ohtake, K.; Takeuchi, Tsutomu; Saito, K.; Ito, T.; Ito, I.; Aoki, K.; Takano, Y.; Amano, K.; Hosono, O.; Koide, J.
In: Internal medicine (Tokyo, Japan), Vol. 32, No. 7, 07.1993, p. 565-568.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Integrin VLA-5 negative primary plasma cell leukemia.
AU - Ohtake, K.
AU - Takeuchi, Tsutomu
AU - Saito, K.
AU - Ito, T.
AU - Ito, I.
AU - Aoki, K.
AU - Takano, Y.
AU - Amano, K.
AU - Hosono, O.
AU - Koide, J.
PY - 1993/7
Y1 - 1993/7
N2 - We present a case of primary plasma cell leukemia with Bence Jones proteinuria. After combination chemotherapy, leukemic cells and the urinary levels Bence Jones protein were decreased. Small lytic bone lesions were detected only in the skull. Typical plasma cells were rarely seen in peripheral blood on the hyperleukocytic phase, however they were increased in the advanced stages. The most important diagnostic sign was persistent expression of CD38 antigen on leukemic cells throughout the entire course of the illness and these leukemic cells expressed very late antigen-4 (VLA-4) but not VLA-5.
AB - We present a case of primary plasma cell leukemia with Bence Jones proteinuria. After combination chemotherapy, leukemic cells and the urinary levels Bence Jones protein were decreased. Small lytic bone lesions were detected only in the skull. Typical plasma cells were rarely seen in peripheral blood on the hyperleukocytic phase, however they were increased in the advanced stages. The most important diagnostic sign was persistent expression of CD38 antigen on leukemic cells throughout the entire course of the illness and these leukemic cells expressed very late antigen-4 (VLA-4) but not VLA-5.
UR - http://www.scopus.com/inward/record.url?scp=0027622003&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027622003&partnerID=8YFLogxK
M3 - Article
C2 - 8286836
AN - SCOPUS:0027622003
VL - 32
SP - 565
EP - 568
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 7
ER -