Integrin VLA-5 negative primary plasma cell leukemia.

K. Ohtake, Tsutomu Takeuchi, K. Saito, T. Ito, I. Ito, K. Aoki, Y. Takano, K. Amano, O. Hosono, J. Koide

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We present a case of primary plasma cell leukemia with Bence Jones proteinuria. After combination chemotherapy, leukemic cells and the urinary levels Bence Jones protein were decreased. Small lytic bone lesions were detected only in the skull. Typical plasma cells were rarely seen in peripheral blood on the hyperleukocytic phase, however they were increased in the advanced stages. The most important diagnostic sign was persistent expression of CD38 antigen on leukemic cells throughout the entire course of the illness and these leukemic cells expressed very late antigen-4 (VLA-4) but not VLA-5.

Original languageEnglish
Pages (from-to)565-568
Number of pages4
JournalInternal medicine (Tokyo, Japan)
Volume32
Issue number7
Publication statusPublished - 1993 Jul
Externally publishedYes

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Plasma Cell Leukemia
Integrin alpha5beta1
Integrins
CD38 Antigens
Bence Jones Protein
Integrin alpha4beta1
Plasma Cells
Combination Drug Therapy
Proteinuria
Skull
Bone and Bones

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Ohtake, K., Takeuchi, T., Saito, K., Ito, T., Ito, I., Aoki, K., ... Koide, J. (1993). Integrin VLA-5 negative primary plasma cell leukemia. Internal medicine (Tokyo, Japan), 32(7), 565-568.

Integrin VLA-5 negative primary plasma cell leukemia. / Ohtake, K.; Takeuchi, Tsutomu; Saito, K.; Ito, T.; Ito, I.; Aoki, K.; Takano, Y.; Amano, K.; Hosono, O.; Koide, J.

In: Internal medicine (Tokyo, Japan), Vol. 32, No. 7, 07.1993, p. 565-568.

Research output: Contribution to journalArticle

Ohtake, K, Takeuchi, T, Saito, K, Ito, T, Ito, I, Aoki, K, Takano, Y, Amano, K, Hosono, O & Koide, J 1993, 'Integrin VLA-5 negative primary plasma cell leukemia.', Internal medicine (Tokyo, Japan), vol. 32, no. 7, pp. 565-568.
Ohtake K, Takeuchi T, Saito K, Ito T, Ito I, Aoki K et al. Integrin VLA-5 negative primary plasma cell leukemia. Internal medicine (Tokyo, Japan). 1993 Jul;32(7):565-568.
Ohtake, K. ; Takeuchi, Tsutomu ; Saito, K. ; Ito, T. ; Ito, I. ; Aoki, K. ; Takano, Y. ; Amano, K. ; Hosono, O. ; Koide, J. / Integrin VLA-5 negative primary plasma cell leukemia. In: Internal medicine (Tokyo, Japan). 1993 ; Vol. 32, No. 7. pp. 565-568.
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