Intra-abdominal desmoid tumor mimicking gastric cancer recurrence

A case report

Akihiko Okamura, Tsunehiro Takahashi, Yoshiro Saikawa, Shuhei Mayanagi, Kazumasa Fukuda, Rieko Nakamura, Norihito Wada, Hirofumi Kawakubo, Tai Omori, Hiroya Takeuchi, Aya Sasaki, Yuukou Kitagawa

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Intra-abdominal desmoid tumors are rare and most often occur in patients with a history of familial adenomatous polyposis, surgery, or pregnancy. We report a case of an intra-abdominal desmoid tumor mimicking the recurrence of gastric cancer. A 57-year-old male had undergone distal gastrectomy for advanced gastric cancer. Serum levels of carcinoembryonic antigen were found to be elevated 27 months after surgery. Computed tomography revealed a 15-mm mass in the mesentery of the transverse colon. In addition, radiotracer fluorodeoxyglucose uptake of the tumor was detected by positron emission tomography. The patient was diagnosed with gastric cancer recurrence, and chemotherapy consisting of cisplatin and S-1 was commenced. After five courses of chemotherapy, although no significant clinical response was seen, no new lesions were seen either. Thus, a curative resection of the recurrent tumor seemed possible, which was successfully performed. Histological examination of the resected specimen revealed spindle-shaped tumor cells with collagen fiber progression; no cancer cells were detected. The tumor was diagnosed as an intra-abdominal desmoid tumor. We report a rare case of an intra-abdominal desmoid tumor that mimicked a recurrent tumor arising from gastric cancer. In patients with history of surgery for intra-abdominal malignancies, it may be difficult to distinguish the recurrence of malignancy from desmoid tumors but the possibility of desmoid tumors must be considered in the differential diagnosis.

Original languageEnglish
Article number146
JournalWorld Journal of Surgical Oncology
Volume12
Issue number1
DOIs
Publication statusPublished - 2014 May 10

Fingerprint

Aggressive Fibromatosis
Stomach Neoplasms
Recurrence
Neoplasms
Drug Therapy
Transverse Colon
Adenomatous Polyposis Coli
Mesentery
Carcinoembryonic Antigen
Gastrectomy
Positron-Emission Tomography

Keywords

  • Desmoid tumor
  • Gastric cancer
  • Recurrence
  • Surgery

ASJC Scopus subject areas

  • Oncology
  • Surgery
  • Medicine(all)

Cite this

Intra-abdominal desmoid tumor mimicking gastric cancer recurrence : A case report. / Okamura, Akihiko; Takahashi, Tsunehiro; Saikawa, Yoshiro; Mayanagi, Shuhei; Fukuda, Kazumasa; Nakamura, Rieko; Wada, Norihito; Kawakubo, Hirofumi; Omori, Tai; Takeuchi, Hiroya; Sasaki, Aya; Kitagawa, Yuukou.

In: World Journal of Surgical Oncology, Vol. 12, No. 1, 146, 10.05.2014.

Research output: Contribution to journalArticle

Okamura, Akihiko ; Takahashi, Tsunehiro ; Saikawa, Yoshiro ; Mayanagi, Shuhei ; Fukuda, Kazumasa ; Nakamura, Rieko ; Wada, Norihito ; Kawakubo, Hirofumi ; Omori, Tai ; Takeuchi, Hiroya ; Sasaki, Aya ; Kitagawa, Yuukou. / Intra-abdominal desmoid tumor mimicking gastric cancer recurrence : A case report. In: World Journal of Surgical Oncology. 2014 ; Vol. 12, No. 1.
@article{7864bf6ada944271b7fbd19a10bb8b7b,
title = "Intra-abdominal desmoid tumor mimicking gastric cancer recurrence: A case report",
abstract = "Intra-abdominal desmoid tumors are rare and most often occur in patients with a history of familial adenomatous polyposis, surgery, or pregnancy. We report a case of an intra-abdominal desmoid tumor mimicking the recurrence of gastric cancer. A 57-year-old male had undergone distal gastrectomy for advanced gastric cancer. Serum levels of carcinoembryonic antigen were found to be elevated 27 months after surgery. Computed tomography revealed a 15-mm mass in the mesentery of the transverse colon. In addition, radiotracer fluorodeoxyglucose uptake of the tumor was detected by positron emission tomography. The patient was diagnosed with gastric cancer recurrence, and chemotherapy consisting of cisplatin and S-1 was commenced. After five courses of chemotherapy, although no significant clinical response was seen, no new lesions were seen either. Thus, a curative resection of the recurrent tumor seemed possible, which was successfully performed. Histological examination of the resected specimen revealed spindle-shaped tumor cells with collagen fiber progression; no cancer cells were detected. The tumor was diagnosed as an intra-abdominal desmoid tumor. We report a rare case of an intra-abdominal desmoid tumor that mimicked a recurrent tumor arising from gastric cancer. In patients with history of surgery for intra-abdominal malignancies, it may be difficult to distinguish the recurrence of malignancy from desmoid tumors but the possibility of desmoid tumors must be considered in the differential diagnosis.",
keywords = "Desmoid tumor, Gastric cancer, Recurrence, Surgery",
author = "Akihiko Okamura and Tsunehiro Takahashi and Yoshiro Saikawa and Shuhei Mayanagi and Kazumasa Fukuda and Rieko Nakamura and Norihito Wada and Hirofumi Kawakubo and Tai Omori and Hiroya Takeuchi and Aya Sasaki and Yuukou Kitagawa",
year = "2014",
month = "5",
day = "10",
doi = "10.1186/1477-7819-12-146",
language = "English",
volume = "12",
journal = "World Journal of Surgical Oncology",
issn = "1477-7819",
publisher = "BioMed Central",
number = "1",

}

TY - JOUR

T1 - Intra-abdominal desmoid tumor mimicking gastric cancer recurrence

T2 - A case report

AU - Okamura, Akihiko

AU - Takahashi, Tsunehiro

AU - Saikawa, Yoshiro

AU - Mayanagi, Shuhei

AU - Fukuda, Kazumasa

AU - Nakamura, Rieko

AU - Wada, Norihito

AU - Kawakubo, Hirofumi

AU - Omori, Tai

AU - Takeuchi, Hiroya

AU - Sasaki, Aya

AU - Kitagawa, Yuukou

PY - 2014/5/10

Y1 - 2014/5/10

N2 - Intra-abdominal desmoid tumors are rare and most often occur in patients with a history of familial adenomatous polyposis, surgery, or pregnancy. We report a case of an intra-abdominal desmoid tumor mimicking the recurrence of gastric cancer. A 57-year-old male had undergone distal gastrectomy for advanced gastric cancer. Serum levels of carcinoembryonic antigen were found to be elevated 27 months after surgery. Computed tomography revealed a 15-mm mass in the mesentery of the transverse colon. In addition, radiotracer fluorodeoxyglucose uptake of the tumor was detected by positron emission tomography. The patient was diagnosed with gastric cancer recurrence, and chemotherapy consisting of cisplatin and S-1 was commenced. After five courses of chemotherapy, although no significant clinical response was seen, no new lesions were seen either. Thus, a curative resection of the recurrent tumor seemed possible, which was successfully performed. Histological examination of the resected specimen revealed spindle-shaped tumor cells with collagen fiber progression; no cancer cells were detected. The tumor was diagnosed as an intra-abdominal desmoid tumor. We report a rare case of an intra-abdominal desmoid tumor that mimicked a recurrent tumor arising from gastric cancer. In patients with history of surgery for intra-abdominal malignancies, it may be difficult to distinguish the recurrence of malignancy from desmoid tumors but the possibility of desmoid tumors must be considered in the differential diagnosis.

AB - Intra-abdominal desmoid tumors are rare and most often occur in patients with a history of familial adenomatous polyposis, surgery, or pregnancy. We report a case of an intra-abdominal desmoid tumor mimicking the recurrence of gastric cancer. A 57-year-old male had undergone distal gastrectomy for advanced gastric cancer. Serum levels of carcinoembryonic antigen were found to be elevated 27 months after surgery. Computed tomography revealed a 15-mm mass in the mesentery of the transverse colon. In addition, radiotracer fluorodeoxyglucose uptake of the tumor was detected by positron emission tomography. The patient was diagnosed with gastric cancer recurrence, and chemotherapy consisting of cisplatin and S-1 was commenced. After five courses of chemotherapy, although no significant clinical response was seen, no new lesions were seen either. Thus, a curative resection of the recurrent tumor seemed possible, which was successfully performed. Histological examination of the resected specimen revealed spindle-shaped tumor cells with collagen fiber progression; no cancer cells were detected. The tumor was diagnosed as an intra-abdominal desmoid tumor. We report a rare case of an intra-abdominal desmoid tumor that mimicked a recurrent tumor arising from gastric cancer. In patients with history of surgery for intra-abdominal malignancies, it may be difficult to distinguish the recurrence of malignancy from desmoid tumors but the possibility of desmoid tumors must be considered in the differential diagnosis.

KW - Desmoid tumor

KW - Gastric cancer

KW - Recurrence

KW - Surgery

UR - http://www.scopus.com/inward/record.url?scp=84900345773&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84900345773&partnerID=8YFLogxK

U2 - 10.1186/1477-7819-12-146

DO - 10.1186/1477-7819-12-146

M3 - Article

VL - 12

JO - World Journal of Surgical Oncology

JF - World Journal of Surgical Oncology

SN - 1477-7819

IS - 1

M1 - 146

ER -