Intracellular activation of acetyl-CoA by an artificial reaction promoter and its fluorescent detection

Hirokazu Komatsu, Yutaka Shindo, Shigehiro A. Kawashima, Kenzo Yamatsugu, Kotaro Oka, Motomu Kanai

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The application of a new rhodamine-based fluorescent probe, RH-NH 23 and an acyl transfer promoter, PBu3, to Hela cells induced a time-dependent increase in fluorescence in the mitochondria, which was most likely due to acetylation of RH-NH23 with activated acetyl-CoA by the artificial reaction promoter in living cells. This journal is

Original languageEnglish
Pages (from-to)2876-2878
Number of pages3
JournalChemical Communications
Volume49
Issue number28
DOIs
Publication statusPublished - 2013 Apr 11

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ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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