Intracerebral hemorrhage due to venous thrombosis of developmental venous anomaly during pregnancy

Morinobu Seki, Mamoru Shibata, Yoshiaki Itoh, Norihiro Suzuki

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background Nowadays, developmental venous anomaly (DVA) is recognized as the most common cerebral vascular malformation. Most DVAs are diagnosed incidentally on routine brain imaging, but they are occasionally symptomatic. We report the case of a 26-year-old Japanese woman with intracerebral hemorrhage due to venous thrombosis of DVA. Methods We examined her neurologic examinations carefully. We also observed her laboratory data, brain computed tomography (CT), and magnetic resonance imaging (MRI) findings. Results She was 8 weeks pregnant and suffered from nausea, vomiturition, and appetite loss because of hyperemesis gravidarum. She presented with a sudden generalized seizure and was referred to our hospital. Brain CT showed a small hemorrhage and a tubular high-density structure compatible with an acutely thrombosed collecting vein in the right frontal lobe. T2∗-weighted MRI also revealed a thrombosed collecting vein along with multiple medullary veins, which looked like caput medusa. She was diagnosed with an intracerebral hemorrhage and symptomatic epilepsy secondary to thrombosis of the DVA. After the acute phase of the disease, systemic anticoagulation therapy was administered to the patient to prevent the recurrence of venous thrombosis. We suspected that hyperemesis gravidarum with intravascular dehydration might have increased the risk of thrombosis in this patient. Conclusions Thrombosis of the collecting vein of DVA is extremely rare. This is the first report regarding DVA thrombosis during pregnancy, to our knowledge.

Original languageEnglish
Pages (from-to)e185-e187
JournalJournal of Stroke and Cerebrovascular Diseases
Volume24
Issue number7
DOIs
Publication statusPublished - 2015 Jul 1

Fingerprint

Cerebral Hemorrhage
Venous Thrombosis
Veins
Thrombosis
Hyperemesis Gravidarum
Pregnancy
Tomography
Magnetic Resonance Imaging
Vascular Malformations
Neurologic Examination
Brain
Frontal Lobe
Acute Disease
Appetite
Dehydration
Neuroimaging
Nausea
Epilepsy
Seizures
Hemorrhage

Keywords

  • Developmental venous anomaly
  • hemorrhage
  • pregnancy
  • venous thrombosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Rehabilitation
  • Cardiology and Cardiovascular Medicine

Cite this

Intracerebral hemorrhage due to venous thrombosis of developmental venous anomaly during pregnancy. / Seki, Morinobu; Shibata, Mamoru; Itoh, Yoshiaki; Suzuki, Norihiro.

In: Journal of Stroke and Cerebrovascular Diseases, Vol. 24, No. 7, 01.07.2015, p. e185-e187.

Research output: Contribution to journalArticle

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