Intrapulmonary metastases in the 7th edition of the TNM classification for lung and pleural tumors

Kanji Nagai, Junji Yoshida, Keiju Aokage, Tomoyuki Hishida, Mitsuyo Nishimura, Genichirou Ishii

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Abstract

The classification of intrapulmonary metastasis (PM), and its impact on T and M stages has been substantially modified in the 7th edition of the TNM classification for lung and pleural tumors. A separate tumor nodule(s) in the same lobe as the primary tumor is defined as PM1. When PM1 is observed, the primary tumor is now staged as T3, which was previously T4 in the 6th edition. A separate tumor nodule(s) in a different ipsilateral lobe to that of the primary tumor is defined as PM2. When PM2 is observed, the primary tumor is staged as T4. A separate tumor nodule(s) in a contralateral lobe is defined as PM3. When PM3 is observed, the disease is staged as M1a. In the new classification, T4N0M0 and T4N1M0 are both staged as IIIA, and T4N2M0 as IIIB. These modifications have resulted in a clearer differentiation of outcome between stages, which supports the validity of the new classification of intrapulmonary metastases.

Original languageEnglish
Pages (from-to)90-93
Number of pages4
JournalJapanese Journal of Lung Cancer
Volume52
Issue number1
DOIs
Publication statusPublished - 2012 Feb 1
Externally publishedYes

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Keywords

  • Intrapulmonary metastases
  • Lung cancer
  • Separate nodule
  • TNM classification

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

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