Investigation of the relationship between position of brain activity and change in optical density for NIR imaging

Yoshihiko Kashio, Muneo Ono, Michael Firbank, Martin Schweiger, Simon R. Arridge, Eiji Okada

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Multi-channel NIR system can obtain the topographic image of brain activity. Since the image is reconstructed from the change in optical density measured with the source-detector pairs, it is important to reveal the volume of tissue sampled by each source-detector pair. In this study, the light propagation in three-dimensional adult head model is calculated by hybrid radiosity-diffusion method. The model is a layered slab which mimics the extra cerebral tissue (skin, skull), CSF and brain. The change in optical density caused by the absorption change in a small cylindrical region of 10 mm in diameter at various positions in the brain is calculated. The greatest change in optical density can be observed when the absorber is located in the middle of the source and detector. When the absorber is located just below the source or detector, the change in optical density is almost half of that caused by the same absorber in the midpoint. The light propagation in the brain is strongly affected by the presence of non-scattering layer and consequently sensitive region is broadly distributed on the brain surface.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages83-90
Number of pages8
Volume4160
DOIs
Publication statusPublished - 2000
EventPhoton Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment - Amsterdam, Neth
Duration: 2000 Jul 62000 Jul 8

Other

OtherPhoton Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment
CityAmsterdam, Neth
Period00/7/600/7/8

Fingerprint

Density (optical)
optical density
brain
Brain
Imaging techniques
Detectors
absorbers
Light propagation
detectors
Tissue
skull
propagation
Skin
slabs

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Kashio, Y., Ono, M., Firbank, M., Schweiger, M., Arridge, S. R., & Okada, E. (2000). Investigation of the relationship between position of brain activity and change in optical density for NIR imaging. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4160, pp. 83-90). Society of Photo-Optical Instrumentation Engineers. https://doi.org/10.1117/12.407612

Investigation of the relationship between position of brain activity and change in optical density for NIR imaging. / Kashio, Yoshihiko; Ono, Muneo; Firbank, Michael; Schweiger, Martin; Arridge, Simon R.; Okada, Eiji.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4160 Society of Photo-Optical Instrumentation Engineers, 2000. p. 83-90.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kashio, Y, Ono, M, Firbank, M, Schweiger, M, Arridge, SR & Okada, E 2000, Investigation of the relationship between position of brain activity and change in optical density for NIR imaging. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 4160, Society of Photo-Optical Instrumentation Engineers, pp. 83-90, Photon Migration, Diffuse Spectroscopy, and Optical Coherence Tomography: Imaging and Functional Assessment, Amsterdam, Neth, 00/7/6. https://doi.org/10.1117/12.407612
Kashio Y, Ono M, Firbank M, Schweiger M, Arridge SR, Okada E. Investigation of the relationship between position of brain activity and change in optical density for NIR imaging. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4160. Society of Photo-Optical Instrumentation Engineers. 2000. p. 83-90 https://doi.org/10.1117/12.407612
Kashio, Yoshihiko ; Ono, Muneo ; Firbank, Michael ; Schweiger, Martin ; Arridge, Simon R. ; Okada, Eiji. / Investigation of the relationship between position of brain activity and change in optical density for NIR imaging. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4160 Society of Photo-Optical Instrumentation Engineers, 2000. pp. 83-90
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