Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

An ortho-selective C−H alkylation of aromatic ketones with N-alkenylindoles proceeded in the presence of just a Fe(PMe3)4 catalyst. In addition, C−H indolylation products, which are considered to be formed via 1,4-iron migration, were also observed as minor products.

Original languageEnglish
JournalAsian Journal of Organic Chemistry
DOIs
Publication statusPublished - 2019 Jan 1

Fingerprint

Alkylation
Ketones
Iron
Catalysts

Keywords

  • alkylation
  • C−H activation
  • heterocycles
  • iron
  • ketones

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

@article{56aaa45040a04f25b84fa1462cd7eb07,
title = "Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration",
abstract = "An ortho-selective C−H alkylation of aromatic ketones with N-alkenylindoles proceeded in the presence of just a Fe(PMe3)4 catalyst. In addition, C−H indolylation products, which are considered to be formed via 1,4-iron migration, were also observed as minor products.",
keywords = "alkylation, C−H activation, heterocycles, iron, ketones",
author = "Naoki Kimura and Takuya Kochi and Fumitoshi Kakiuchi",
year = "2019",
month = "1",
day = "1",
doi = "10.1002/ajoc.201900209",
language = "English",
journal = "Asian Journal of Organic Chemistry",
issn = "2193-5807",
publisher = "Wiley - VCH Verlag GmbH & CO. KGaA",

}

TY - JOUR

T1 - Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration

AU - Kimura, Naoki

AU - Kochi, Takuya

AU - Kakiuchi, Fumitoshi

PY - 2019/1/1

Y1 - 2019/1/1

N2 - An ortho-selective C−H alkylation of aromatic ketones with N-alkenylindoles proceeded in the presence of just a Fe(PMe3)4 catalyst. In addition, C−H indolylation products, which are considered to be formed via 1,4-iron migration, were also observed as minor products.

AB - An ortho-selective C−H alkylation of aromatic ketones with N-alkenylindoles proceeded in the presence of just a Fe(PMe3)4 catalyst. In addition, C−H indolylation products, which are considered to be formed via 1,4-iron migration, were also observed as minor products.

KW - alkylation

KW - C−H activation

KW - heterocycles

KW - iron

KW - ketones

UR - http://www.scopus.com/inward/record.url?scp=85067398535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85067398535&partnerID=8YFLogxK

U2 - 10.1002/ajoc.201900209

DO - 10.1002/ajoc.201900209

M3 - Article

JO - Asian Journal of Organic Chemistry

JF - Asian Journal of Organic Chemistry

SN - 2193-5807

ER -