Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration

Naoki Kimura, Takuya Kochi, Fumitoshi Kakiuchi

Research output: Contribution to journal › Article

1 Citation (Scopus)

Abstract

An ortho-selective C−H alkylation of aromatic ketones with N-alkenylindoles proceeded in the presence of just a Fe(PMe3)4 catalyst. In addition, C−H indolylation products, which are considered to be formed via 1,4-iron migration, were also observed as minor products.

Original languageEnglish
JournalAsian Journal of Organic Chemistry
DOIs
Publication statusPublished - 2019 Jan 1

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Alkylation
Ketones
Iron
Catalysts

Keywords

  • alkylation
  • C−H activation
  • heterocycles
  • iron
  • ketones

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration. / Kimura, Naoki; Kochi, Takuya; Kakiuchi, Fumitoshi.

In: Asian Journal of Organic Chemistry, 01.01.2019.

Research output: Contribution to journal › Article

Kimura, N, Kochi, T & Kakiuchi, F 2019, 'Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration', Asian Journal of Organic Chemistry. https://doi.org/10.1002/ajoc.201900209
Kimura N, Kochi T, Kakiuchi F. Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration. Asian Journal of Organic Chemistry. 2019 Jan 1. https://doi.org/10.1002/ajoc.201900209
Kimura, Naoki ; Kochi, Takuya ; Kakiuchi, Fumitoshi. / Iron-Catalyzed Ortho-Selective C−H Alkylation of Aromatic Ketones with N-Alkenylindoles and Partial Indolylation via 1,4-Iron Migration. In: Asian Journal of Organic Chemistry. 2019.
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