Irreversible aggregation of alternating tetra-block-like amphiphile in water

Shota Konno, Taisuke Banno, Hideaki Takagi, Satoshi Honda, Taro Toyota

Research output: Contribution to journalArticle

Abstract

As a frontier topic of soft condensed matter physics, irreversible aggregation has drawn attention for a better understanding of the complex behavior of biomaterials. In this study, we have described the synthesis of an artificial amphiphilic molecule, an alternating tetra-block-like amphiphile, which was able to diversify its aggregate structure in water. The aggregated state of its aqueous dispersion was obtained by slow evaporation of the organic solvent at room temperature, and it collapsed irreversibly at ~ 50C. By using a cryo-trans-mission electron microscope and a differential scanning calorimeter, it was revealed that two types of molecular nanostructures were formed and developed into submicro- and micrometer-sized fibrils in the aggregated material.

Original languageEnglish
Article numbere0202816
JournalPLoS One
Volume13
Issue number8
DOIs
Publication statusPublished - 2018 Aug 1

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Condensed matter physics
Amphiphiles
Nanostructures
Physics
Biocompatible Materials
Calorimeters
Organic solvents
Evaporation
Electron microscopes
Agglomeration
Electrons
Scanning
nanomaterials
biocompatible materials
calorimeters
Molecules
Temperature
Water
electron microscopes
physics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Irreversible aggregation of alternating tetra-block-like amphiphile in water. / Konno, Shota; Banno, Taisuke; Takagi, Hideaki; Honda, Satoshi; Toyota, Taro.

In: PLoS One, Vol. 13, No. 8, e0202816, 01.08.2018.

Research output: Contribution to journalArticle

Konno, Shota ; Banno, Taisuke ; Takagi, Hideaki ; Honda, Satoshi ; Toyota, Taro. / Irreversible aggregation of alternating tetra-block-like amphiphile in water. In: PLoS One. 2018 ; Vol. 13, No. 8.
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