Is canalization more than just a beautiful idea?

Kaoru Sato, Haruhiko Siomi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The heat-shock protein 90 (Hsp90) is currently thought to buffer eukaryotic cells against perturbations caused by pre-existing cryptic genetic variation. A new study suggests that the buffering function of Hsp90 could instead be due to its repression of de novo transposon-mediated mutagenesis.

Original languageEnglish
Article number109
JournalGenome Biology
Volume11
Issue number3
DOIs
Publication statusPublished - 2010 Mar 16

Fingerprint

HSP90 Heat-Shock Proteins
heat shock
protein
Eukaryotic Cells
buffering
mutagenesis
Mutagenesis
transposons
eukaryotic cells
genetic variation
Buffers
buffers
perturbation
heat-shock protein 90
repression

ASJC Scopus subject areas

  • Genetics
  • Cell Biology
  • Ecology, Evolution, Behavior and Systematics

Cite this

Is canalization more than just a beautiful idea? / Sato, Kaoru; Siomi, Haruhiko.

In: Genome Biology, Vol. 11, No. 3, 109, 16.03.2010.

Research output: Contribution to journalArticle

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