Diffuse mesangial sclerosis is a rare renal disease, occurring either in isolation or as part of Denys-Drash syndrome. Denys-Drash syndrome originates from mutations of the Wilms tumor suppressor gene (WT1). We describe the presence of WT1 mutations in 7 Japanese children with isolated diffuse mesangial sclerosis.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health