Isolation and biosynthetic pathway for citreohybridones from the hybrid strain KO 0031 derived from Penicillium species

Seiji Kosemura, Shosuke Yamamura

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Five new metabolites, citreohybridones D - G and isocitreohybridone G, have been isolated from the mycelium of the hybrid strain KO 0031 derived from Penicillium citreo-viride B. IFO 6200 and 4692. Their stereostructures have been also elucidated on the basis of their spectral data and some chemical evidence, and a biosynthetic pathway for citreohybridones is proposed.

Original languageEnglish
Pages (from-to)6221-6224
Number of pages4
JournalTetrahedron Letters
Issue number35
Publication statusPublished - 1997 Sep 1


ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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