Isolation and structures of hedaols A, B, and C, new bisnorditerpenes from a Japanese brown alga

Noboru Takada; Reiko Watanabe; Kiyotake Suenaga; Kaoru Yamada; Daisuke Uemura

doi:10.1021/np0005661

Isolation and structures of hedaols A, B, and C, new bisnorditerpenes from a Japanese brown alga

Noboru Takada, Reiko Watanabe, Kiyotake Suenaga, Kaoru Yamada, Daisuke Uemura

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

New bisnorditerpenes, hedaols A (1), B (2), and C (3), were isolated from the Japanese brown alga Sargassum sp. Their structures were determined by spectroscopic analysis. The absolute stereocenter of 1 was determined by the modified Mosher's method. Hedaols showed low cytotoxicity against P388 cells.

Original language	English
Pages (from-to)	653-655
Number of pages	3
Journal	Journal of Natural Products
Volume	64
Issue number	5
DOIs	https://doi.org/10.1021/np0005661
Publication status	Published - 2001 May 1
Externally published	Yes

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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10.1021/np0005661

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AU - Takada, Noboru

AU - Watanabe, Reiko

AU - Suenaga, Kiyotake

AU - Yamada, Kaoru

AU - Uemura, Daisuke

PY - 2001/5/1

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AB - New bisnorditerpenes, hedaols A (1), B (2), and C (3), were isolated from the Japanese brown alga Sargassum sp. Their structures were determined by spectroscopic analysis. The absolute stereocenter of 1 was determined by the modified Mosher's method. Hedaols showed low cytotoxicity against P388 cells.

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Isolation and structures of hedaols A, B, and C, new bisnorditerpenes from a Japanese brown alga

Abstract

ASJC Scopus subject areas

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