Isolation of inohanalactone, a γ-butyrolactone, from Nocardia Inohanensis IFM0092T

Natsumi Kobayashi, Yasumasa Hara, Midori A. Arai, Shoko Hara, Tohru Gonoi, Takashi Yaguchi, Masami Ishibashi

Research output: Contribution to journalArticle

Abstract

Because research on the genus Nocardia has not progressed as compared to the extensively studied genus Streptomyces, Nocardia is considered as a useful undeveloped resource for exploring natural products. In this study, a new γ-butyrolactone derivative, named inohanalactone (1), was isolated from Nocardia inohanensis IFM0092T. Inohanalactone possesses an aliphatic side chain containing 8 carbons, a vicinal diol, and a cis double bond. Inohanalactone was produced by N. inohanensis IFM0092T in the modified Czapek-Dox medium, whereas it was not produced in other media such as Nutrient broth, Waksman, and Yeast-Malt-Glucose media.

Original languageEnglish
Pages (from-to)312-317
Number of pages6
JournalHeterocycles
Volume101
Issue number1
DOIs
Publication statusPublished - 2020 Jan 1
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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    Kobayashi, N., Hara, Y., Arai, M. A., Hara, S., Gonoi, T., Yaguchi, T., & Ishibashi, M. (2020). Isolation of inohanalactone, a γ-butyrolactone, from Nocardia Inohanensis IFM0092T Heterocycles, 101(1), 312-317. https://doi.org/10.3987/COM-19-S(F)11