An acetylene-containing lipopeptide, jahanyne, was isolated from the marine cyanobacterium Lyngbya sp. Its gross structure was established by spectroscopic analyses, and the absolute configuration was clarified based on a combination of chiral HPLC analyses, spectroscopic analyses, and derivatization reactions. Jahanyne significantly inhibited the growth of human cancer cells and induced apoptosis in HeLa cells.
|Number of pages||4|
|Publication status||Published - 2015 Feb 6|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry