Japan alcoholic hepatitis score can help management of patients with alcoholic hepatitis

Yoshinori Horie, Yoshiyuki Yamagishi, Hirotoshi Ebinuma, Takanori Kanai

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Ability of a new scoring system for alcoholic hepatitis (AH) (Japan Alcoholic Hepatitis Score: J AS) to predict outcome was confirmed in the data of patients with AH in 2011. Twenty six hospitals provided full demographic data on 59 patients with AH (Moderate 26, Alive 22, Dead 4; Severe 33, Alive 16, Dead 17). There was no report of death in patients with mild AH (J AS score was 7 and less). Prevalence of renal failure, DIC and gastrointestinal bleeding was higher in patients who were died. Cr and PT (INR) were higher in severe AH patients who were died. These results suggest that JAS allows the stratification of the risk of death in AH, and can help the management of patients with AH. If there is any 3 points factor, intensive care such as corticosteroids, granulocytes/monocytes apheresis, plasma exchange and haemodialysis is recommended.

Original languageEnglish
Pages (from-to)22-32
Number of pages11
JournalActa Hepatologica Japonica
Volume55
Issue number1
DOIs
Publication statusPublished - 2014

Fingerprint

Alcoholic Hepatitis
Japan
Dacarbazine
Blood Component Removal
Plasma Exchange
International Normalized Ratio
Critical Care
Granulocytes
Renal Insufficiency
Renal Dialysis
Monocytes
Adrenal Cortex Hormones
Demography
Hemorrhage

Keywords

  • Alcoholic hepatitis
  • Corticosteroids
  • Granulocytes/monocytes apheresis
  • Leukocytapheresis
  • Score

ASJC Scopus subject areas

  • Hepatology

Cite this

Japan alcoholic hepatitis score can help management of patients with alcoholic hepatitis. / Horie, Yoshinori; Yamagishi, Yoshiyuki; Ebinuma, Hirotoshi; Kanai, Takanori.

In: Acta Hepatologica Japonica, Vol. 55, No. 1, 2014, p. 22-32.

Research output: Contribution to journalArticle

Horie, Yoshinori ; Yamagishi, Yoshiyuki ; Ebinuma, Hirotoshi ; Kanai, Takanori. / Japan alcoholic hepatitis score can help management of patients with alcoholic hepatitis. In: Acta Hepatologica Japonica. 2014 ; Vol. 55, No. 1. pp. 22-32.
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