Keeping DCs awake by putting SOCS1 to sleep

Takashi Kobayashi; Akihiko Yoshimura

doi:10.1016/j.it.2005.02.004

Keeping DCs awake by putting SOCS1 to sleep

Takashi Kobayashi, Akihiko Yoshimura

Research output: Contribution to journal › Short survey › peer-review

28 Citations (Scopus)

Abstract

It has recently been shown that small interfering RNA (siRNA)-mediated inhibition of suppressors of cytokine signalling 1 (SOCS1) function enhances the immunostimulatory capacity of dendritic cells (DCs), which leads to more effective cancer vaccination. This recent study demonstrates the importance of negative regulation of DC maturation and functions for DC-based immunotherapy.

Original language	English
Pages (from-to)	177-179
Number of pages	3
Journal	Trends in Immunology
Volume	26
Issue number	4
DOIs	https://doi.org/10.1016/j.it.2005.02.004
Publication status	Published - 2005 Apr
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.it.2005.02.004

Cite this

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title = "Keeping DCs awake by putting SOCS1 to sleep",

abstract = "It has recently been shown that small interfering RNA (siRNA)-mediated inhibition of suppressors of cytokine signalling 1 (SOCS1) function enhances the immunostimulatory capacity of dendritic cells (DCs), which leads to more effective cancer vaccination. This recent study demonstrates the importance of negative regulation of DC maturation and functions for DC-based immunotherapy.",

author = "Takashi Kobayashi and Akihiko Yoshimura",

year = "2005",

month = apr,

doi = "10.1016/j.it.2005.02.004",

language = "English",

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journal = "Trends in Immunology",

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AU - Kobayashi, Takashi

AU - Yoshimura, Akihiko

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AB - It has recently been shown that small interfering RNA (siRNA)-mediated inhibition of suppressors of cytokine signalling 1 (SOCS1) function enhances the immunostimulatory capacity of dendritic cells (DCs), which leads to more effective cancer vaccination. This recent study demonstrates the importance of negative regulation of DC maturation and functions for DC-based immunotherapy.

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U2 - 10.1016/j.it.2005.02.004

DO - 10.1016/j.it.2005.02.004

M3 - Short survey

C2 - 15797506

AN - SCOPUS:20044377801

SN - 1471-4906

VL - 26

SP - 177

EP - 179

JO - Trends in Immunology

JF - Trends in Immunology

IS - 4

ER -

Keeping DCs awake by putting SOCS1 to sleep

Abstract

ASJC Scopus subject areas

UN SDGs

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