Kinetics of dimension-restricted conditions

Noriko Hiroi, Akira Funahashi

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

The intracellular environment is crowded with skeletal proteins, organelle membranes, ribosomes, and so on. When molecular movement is restricted by such environments, some biochemical reaction processes cannot be represented by classical models, which assume that reactions occur in simple Newtonian fluids. Dimension-restricted reaction kinetics (DRRK) modeling is a method that can represent dimension-restricted reactions. We introduce the methods of DRRK in each case of reaction type. DRRK has another advantage in that it can be quantitatively evaluated by biochemical experiments. We also introduce the procedure of applying it for experimental results. This modeling method may provide the basis for in vivo-oriented modeling.

Original languageEnglish
Title of host publicationIntroduction to Systems Biology
PublisherHumana Press
Pages261-281
Number of pages21
ISBN (Print)9781588297068
DOIs
Publication statusPublished - 2007 Dec 1

Keywords

  • Fractal kinetics
  • percolation theory

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Hiroi, N., & Funahashi, A. (2007). Kinetics of dimension-restricted conditions. In Introduction to Systems Biology (pp. 261-281). Humana Press. https://doi.org/10.1007/978-1-59745-531-2_14