Kinetics of dimension-restricted conditions

Noriko Hiroi; Akira Funahashi

doi:10.1007/978-1-59745-531-2_14

Kinetics of dimension-restricted conditions

Noriko Hiroi, Akira Funahashi

Department of Biosciences and Informatics

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Citations (Scopus)

Abstract

The intracellular environment is crowded with skeletal proteins, organelle membranes, ribosomes, and so on. When molecular movement is restricted by such environments, some biochemical reaction processes cannot be represented by classical models, which assume that reactions occur in simple Newtonian fluids. Dimension-restricted reaction kinetics (DRRK) modeling is a method that can represent dimension-restricted reactions. We introduce the methods of DRRK in each case of reaction type. DRRK has another advantage in that it can be quantitatively evaluated by biochemical experiments. We also introduce the procedure of applying it for experimental results. This modeling method may provide the basis for in vivo-oriented modeling.

Original language	English
Title of host publication	Introduction to Systems Biology
Publisher	Humana Press
Pages	261-281
Number of pages	21
ISBN (Print)	9781588297068
DOIs	https://doi.org/10.1007/978-1-59745-531-2_14
Publication status	Published - 2007 Dec 1

Keywords

Fractal kinetics
percolation theory

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1007/978-1-59745-531-2_14

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Kinetics of dimension-restricted conditions

Abstract

Keywords

ASJC Scopus subject areas

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