Kohamaic acids A and B, novel cytotoxic sesterterpenic acids, from the marine sponge Ircinia sp

Susumu Kokubo, Kentaro Yogi, Md Jasim Uddin, Toshiyasu Inuzuka, Kiyotake Suenaga, Katsuhiro Ueda, Daisuke Uemura

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Abstract

Two new sesterterpenic acids, which exhibited moderate cytotoxicity, were isolated from the marine sponge Ircinia sp. Their absolute stereochemistries were determined by spectroscopic and chemical analyses. Their configurations at C15 were different from those of previously isolated sesterterpenes. This result suggests the existence of a (14Z)-geranylfarnesyl pyrophosphate, which is yet unknown in nature.

Original languageEnglish
Pages (from-to)176-177
Number of pages2
JournalChemistry Letters
Issue number2
DOIs
Publication statusPublished - 2001 Jan 1
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)

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