Komesuamide and odopenicillatamide, two linear lipopeptides from the marine cyanobacterium Caldora penicillata

Kaori Ozaki, Atsuhide Jinno, Noriyuki Natsume, Shimpei Sumimoto, Arihiro Iwasaki, Kiyotake Suenaga, Toshiaki Teruya

Research output: Contribution to journalArticlepeer-review

Abstract

The linear lipopeptides komesuamide (1) and odopenicillatamide (2) were isolated from Caldora penicillata a marine cyanobacterium collected in Okinawa. The structures of these compounds were established by spectroscopic analyses, and the absolute configurations were determined by HPLC analyses of the acid hydrolysates. Both compounds showed glucose uptake activity at 40 μM in cultured L6 myotubes.

Original languageEnglish
Article number131969
JournalTetrahedron
Volume85
DOIs
Publication statusPublished - 2021 Apr 9

Keywords

  • Caldora penicillata
  • Glucose uptake activity
  • Linear lipopeptide
  • Marine cyanobacteria

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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