Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries

Natsumi Shimazaki, Sho Naruse, Tsunenori Arai, Nobuaki Imanishi, Sadakazu Aiso

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The purpose of this study was to investigate the artery dilatation performance of the short-duration heating balloon catheter in cadaver stenotic arteries. We designed a prototype short-duration heating balloon catheter that can heat artery media to around 60 °C in 15-25 s by a combination of laser-driven heat generation and continuous fluid irrigation in the balloon. We performed ex vivo short-duration heating dilatation in the cadaver atherosclerotic femoral arteries (initial percent diameter stenosis was 36-98%), with the maximum balloon temperature of 65±5 °C, laser irradiation duration of 25 s, and balloon dilatation pressure of 3.5 atm. The artery lumen configurations before and after the dilatations were assessed with a commercial IVUS system. After the short-duration heating dilatations, the percent diameter stenosis was reduced below 30% without any artery tears or dissections. We estimated that the artery media temperature was raised to around 60 °C in which plaque thickness was below 0.8 mm by a thermal conduction calculation. The estimated maximum temperature in artery adventitia and surrounding tissue was up to 45 °C. We found that the short-duration heating balloon could sufficiently dilate the cadaver stenotic arteries, without thermal injury in artery adventitia and surroundings.

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8565
DOIs
Publication statusPublished - 2013
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: 2013 Feb 22013 Feb 7

Other

OtherPhotonic Therapeutics and Diagnostics IX
CountryUnited States
CitySan Francisco, CA
Period13/2/213/2/7

Fingerprint

Balloons
Femoral Artery
arteries
Angioplasty
Cadaver
Heating
Dilatation
Lasers
Arteries
balloons
heating
lasers
Catheters
Hot Temperature
Adventitia
Dissection
Temperature
Heat generation
Pathologic Constriction
Laser beam effects

Keywords

  • Balloon angioplasty
  • Extracted human cadaver artery
  • Thermal angioplasty

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Shimazaki, N., Naruse, S., Arai, T., Imanishi, N., & Aiso, S. (2013). Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8565). [85654E] https://doi.org/10.1117/12.2005432

Laser-driven short-duration heating angioplasty : Dilatation performance in cadaver atherosclerotic femoral arteries. / Shimazaki, Natsumi; Naruse, Sho; Arai, Tsunenori; Imanishi, Nobuaki; Aiso, Sadakazu.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013. 85654E.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shimazaki, N, Naruse, S, Arai, T, Imanishi, N & Aiso, S 2013, Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8565, 85654E, Photonic Therapeutics and Diagnostics IX, San Francisco, CA, United States, 13/2/2. https://doi.org/10.1117/12.2005432
Shimazaki N, Naruse S, Arai T, Imanishi N, Aiso S. Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565. 2013. 85654E https://doi.org/10.1117/12.2005432
Shimazaki, Natsumi ; Naruse, Sho ; Arai, Tsunenori ; Imanishi, Nobuaki ; Aiso, Sadakazu. / Laser-driven short-duration heating angioplasty : Dilatation performance in cadaver atherosclerotic femoral arteries. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013.
@inproceedings{a22ce58bb00746499cf7013567fb263e,
title = "Laser-driven short-duration heating angioplasty: Dilatation performance in cadaver atherosclerotic femoral arteries",
abstract = "The purpose of this study was to investigate the artery dilatation performance of the short-duration heating balloon catheter in cadaver stenotic arteries. We designed a prototype short-duration heating balloon catheter that can heat artery media to around 60 °C in 15-25 s by a combination of laser-driven heat generation and continuous fluid irrigation in the balloon. We performed ex vivo short-duration heating dilatation in the cadaver atherosclerotic femoral arteries (initial percent diameter stenosis was 36-98{\%}), with the maximum balloon temperature of 65±5 °C, laser irradiation duration of 25 s, and balloon dilatation pressure of 3.5 atm. The artery lumen configurations before and after the dilatations were assessed with a commercial IVUS system. After the short-duration heating dilatations, the percent diameter stenosis was reduced below 30{\%} without any artery tears or dissections. We estimated that the artery media temperature was raised to around 60 °C in which plaque thickness was below 0.8 mm by a thermal conduction calculation. The estimated maximum temperature in artery adventitia and surrounding tissue was up to 45 °C. We found that the short-duration heating balloon could sufficiently dilate the cadaver stenotic arteries, without thermal injury in artery adventitia and surroundings.",
keywords = "Balloon angioplasty, Extracted human cadaver artery, Thermal angioplasty",
author = "Natsumi Shimazaki and Sho Naruse and Tsunenori Arai and Nobuaki Imanishi and Sadakazu Aiso",
year = "2013",
doi = "10.1117/12.2005432",
language = "English",
isbn = "9780819493347",
volume = "8565",
booktitle = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

}

TY - GEN

T1 - Laser-driven short-duration heating angioplasty

T2 - Dilatation performance in cadaver atherosclerotic femoral arteries

AU - Shimazaki, Natsumi

AU - Naruse, Sho

AU - Arai, Tsunenori

AU - Imanishi, Nobuaki

AU - Aiso, Sadakazu

PY - 2013

Y1 - 2013

N2 - The purpose of this study was to investigate the artery dilatation performance of the short-duration heating balloon catheter in cadaver stenotic arteries. We designed a prototype short-duration heating balloon catheter that can heat artery media to around 60 °C in 15-25 s by a combination of laser-driven heat generation and continuous fluid irrigation in the balloon. We performed ex vivo short-duration heating dilatation in the cadaver atherosclerotic femoral arteries (initial percent diameter stenosis was 36-98%), with the maximum balloon temperature of 65±5 °C, laser irradiation duration of 25 s, and balloon dilatation pressure of 3.5 atm. The artery lumen configurations before and after the dilatations were assessed with a commercial IVUS system. After the short-duration heating dilatations, the percent diameter stenosis was reduced below 30% without any artery tears or dissections. We estimated that the artery media temperature was raised to around 60 °C in which plaque thickness was below 0.8 mm by a thermal conduction calculation. The estimated maximum temperature in artery adventitia and surrounding tissue was up to 45 °C. We found that the short-duration heating balloon could sufficiently dilate the cadaver stenotic arteries, without thermal injury in artery adventitia and surroundings.

AB - The purpose of this study was to investigate the artery dilatation performance of the short-duration heating balloon catheter in cadaver stenotic arteries. We designed a prototype short-duration heating balloon catheter that can heat artery media to around 60 °C in 15-25 s by a combination of laser-driven heat generation and continuous fluid irrigation in the balloon. We performed ex vivo short-duration heating dilatation in the cadaver atherosclerotic femoral arteries (initial percent diameter stenosis was 36-98%), with the maximum balloon temperature of 65±5 °C, laser irradiation duration of 25 s, and balloon dilatation pressure of 3.5 atm. The artery lumen configurations before and after the dilatations were assessed with a commercial IVUS system. After the short-duration heating dilatations, the percent diameter stenosis was reduced below 30% without any artery tears or dissections. We estimated that the artery media temperature was raised to around 60 °C in which plaque thickness was below 0.8 mm by a thermal conduction calculation. The estimated maximum temperature in artery adventitia and surrounding tissue was up to 45 °C. We found that the short-duration heating balloon could sufficiently dilate the cadaver stenotic arteries, without thermal injury in artery adventitia and surroundings.

KW - Balloon angioplasty

KW - Extracted human cadaver artery

KW - Thermal angioplasty

UR - http://www.scopus.com/inward/record.url?scp=84878207479&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84878207479&partnerID=8YFLogxK

U2 - 10.1117/12.2005432

DO - 10.1117/12.2005432

M3 - Conference contribution

AN - SCOPUS:84878207479

SN - 9780819493347

VL - 8565

BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

ER -