TY - JOUR
T1 - Late contrast-enhanced CT for small pancreatic carcinoma
T2 - Delayed enhanced area on CT with histopathological correlation
AU - Furukawa, Hiroyoshi
AU - Takayasu, Kenichi
AU - Mukai, Kiyoshi
AU - Kanai, Yae
AU - Inoue, Kazuto
AU - Kosuge, Tomoo
AU - Ushio, Kyosuke
PY - 1996/11/6
Y1 - 1996/11/6
N2 - Purpose: To determine the appearance of pancreatic adenocarcinoma on delayed contrast enhanced computed tomography (CT) and verify the diagnostic significance. Patients and Methods: Twenty-two surgically resected lesions of pancreatic adenocarcinoma were studied with dynamic CT and findings were compared with those on histopathology. Results: Ten 45% of 22 pancreatic adenocarcinoma demonstrated masses on unenhanced CT, while 21 (95%) demonstrated on early contrast-enhanced CT (early CT), and 15 (68%) demonstrated masses on delayed contrast-enhanced CT (late CT). Pancreatic mass was demonstrated as a low-density area on unenhanced and early CT, but mass density varied on late CT. Delayed enhancement of the mass was predominantly observed in small lesions; 3 (75%) of 4 lesions 2 cm or smaller were detected as high-density areas. Histologically, delayed enhanced lesions showed severe or moderate degrees of fibrosis. Conclusion: Late CT is useful for the detection of pancreatic adenocarcinoma with fibrosis as a high-density area, especially in small lesions.
AB - Purpose: To determine the appearance of pancreatic adenocarcinoma on delayed contrast enhanced computed tomography (CT) and verify the diagnostic significance. Patients and Methods: Twenty-two surgically resected lesions of pancreatic adenocarcinoma were studied with dynamic CT and findings were compared with those on histopathology. Results: Ten 45% of 22 pancreatic adenocarcinoma demonstrated masses on unenhanced CT, while 21 (95%) demonstrated on early contrast-enhanced CT (early CT), and 15 (68%) demonstrated masses on delayed contrast-enhanced CT (late CT). Pancreatic mass was demonstrated as a low-density area on unenhanced and early CT, but mass density varied on late CT. Delayed enhancement of the mass was predominantly observed in small lesions; 3 (75%) of 4 lesions 2 cm or smaller were detected as high-density areas. Histologically, delayed enhanced lesions showed severe or moderate degrees of fibrosis. Conclusion: Late CT is useful for the detection of pancreatic adenocarcinoma with fibrosis as a high-density area, especially in small lesions.
KW - Computed tomography
KW - Pancreatic carcinoma
KW - Pancreatic neoplasm
KW - Tumor fibrosis
UR - http://www.scopus.com/inward/record.url?scp=0029861009&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029861009&partnerID=8YFLogxK
M3 - Article
C2 - 8908556
AN - SCOPUS:0029861009
VL - 43
SP - 1230
EP - 1237
JO - Acta hepato-splenologica
JF - Acta hepato-splenologica
SN - 0172-6390
IS - 11
ER -