Abstract
Aims: Although lead exposure has, in the absence of mathematical modelling, been believed to elevate blood pressure in females, it is necessary to clarify the relation between lead and blood pressure by eliminating confounding factors in the analysis. Methods: Blood lead was measured in 193 female workers, including 123 lead exposed workers. Possible confounding factors were controlled by multiple regression analyses. Results and Conclusion: Blood lead above 40 μg/dl was found to be the most potent factor for elevating systolic/diastolic blood pressure. Aging, urine protein, and plasma triglyceride also contributed to systolic/diastolic/pulse pressure increase, but hypertensive heredity did not. Data suggested that lead induced changes in lipoprotein metabolism may play an important role in the lead induced blood pressure increase in female workers.
| Original language | English |
|---|---|
| Pages (from-to) | 734-738 |
| Number of pages | 5 |
| Journal | Occupational and Environmental Medicine |
| Volume | 59 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2002 Nov 1 |
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ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
- Environmental Science(all)
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Lead induced increase of blood pressure in female lead workers. / Nomiyama, K.; Nomiyama, H.; Liu, S. J.; Tao, Y. X.; Nomiyama, T.; Omae, K.
In: Occupational and Environmental Medicine, Vol. 59, No. 11, 01.11.2002, p. 734-738.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Lead induced increase of blood pressure in female lead workers
AU - Nomiyama, K.
AU - Nomiyama, H.
AU - Liu, S. J.
AU - Tao, Y. X.
AU - Nomiyama, T.
AU - Omae, K.
PY - 2002/11/1
Y1 - 2002/11/1
N2 - Aims: Although lead exposure has, in the absence of mathematical modelling, been believed to elevate blood pressure in females, it is necessary to clarify the relation between lead and blood pressure by eliminating confounding factors in the analysis. Methods: Blood lead was measured in 193 female workers, including 123 lead exposed workers. Possible confounding factors were controlled by multiple regression analyses. Results and Conclusion: Blood lead above 40 μg/dl was found to be the most potent factor for elevating systolic/diastolic blood pressure. Aging, urine protein, and plasma triglyceride also contributed to systolic/diastolic/pulse pressure increase, but hypertensive heredity did not. Data suggested that lead induced changes in lipoprotein metabolism may play an important role in the lead induced blood pressure increase in female workers.
AB - Aims: Although lead exposure has, in the absence of mathematical modelling, been believed to elevate blood pressure in females, it is necessary to clarify the relation between lead and blood pressure by eliminating confounding factors in the analysis. Methods: Blood lead was measured in 193 female workers, including 123 lead exposed workers. Possible confounding factors were controlled by multiple regression analyses. Results and Conclusion: Blood lead above 40 μg/dl was found to be the most potent factor for elevating systolic/diastolic blood pressure. Aging, urine protein, and plasma triglyceride also contributed to systolic/diastolic/pulse pressure increase, but hypertensive heredity did not. Data suggested that lead induced changes in lipoprotein metabolism may play an important role in the lead induced blood pressure increase in female workers.
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UR - http://www.scopus.com/inward/citedby.url?scp=0036844842&partnerID=8YFLogxK
U2 - 10.1136/oem.59.11.734
DO - 10.1136/oem.59.11.734
M3 - Article
C2 - 12409531
AN - SCOPUS:0036844842
VL - 59
SP - 734
EP - 738
JO - Occupational and Environmental Medicine
JF - Occupational and Environmental Medicine
SN - 1351-0711
IS - 11
ER -