Lead induced increase of blood pressure in female lead workers

K. Nomiyama, H. Nomiyama, S. J. Liu, Y. X. Tao, T. Nomiyama, K. Omae

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Abstract

Aims: Although lead exposure has, in the absence of mathematical modelling, been believed to elevate blood pressure in females, it is necessary to clarify the relation between lead and blood pressure by eliminating confounding factors in the analysis. Methods: Blood lead was measured in 193 female workers, including 123 lead exposed workers. Possible confounding factors were controlled by multiple regression analyses. Results and Conclusion: Blood lead above 40 μg/dl was found to be the most potent factor for elevating systolic/diastolic blood pressure. Aging, urine protein, and plasma triglyceride also contributed to systolic/diastolic/pulse pressure increase, but hypertensive heredity did not. Data suggested that lead induced changes in lipoprotein metabolism may play an important role in the lead induced blood pressure increase in female workers.

Original languageEnglish
Pages (from-to)734-738
Number of pages5
JournalOccupational and Environmental Medicine
Volume59
Issue number11
DOIs
Publication statusPublished - 2002 Nov 1

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ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Environmental Science(all)

Cite this

Nomiyama, K., Nomiyama, H., Liu, S. J., Tao, Y. X., Nomiyama, T., & Omae, K. (2002). Lead induced increase of blood pressure in female lead workers. Occupational and Environmental Medicine, 59(11), 734-738. https://doi.org/10.1136/oem.59.11.734