Abstract
A 78-year-old housewife with major depression developed a right-sided infarction in the territory of the middle cerebral arteries, followed by acute post-stroke mania. Comparison between pre- and post-stroke SPECT scans demonstrated a unique pattern of left orbitofrontal hyperperfusion with extensive right frontal hypoperfusion. A functional imbalance between right and left orbitofrontal cortices may be important in mania.
Original language | English |
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Pages (from-to) | 263-267 |
Number of pages | 5 |
Journal | Psychiatry Research - Neuroimaging |
Volume | 139 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2005 Aug 30 |
Externally published | Yes |
Keywords
- Mood disorder
- Orbitofrontal cortex
- Single photon emission tomography
ASJC Scopus subject areas
- Neuroscience (miscellaneous)
- Radiology Nuclear Medicine and imaging
- Psychiatry and Mental health