Leucocyte distribution during sevoflurane anaesthesia

Hiroshi Morisaki, Y. Aoyama, M. Shimada, R. Ochiai, J. Takeda

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We have examined if sevoflurane anaesthesia per se modified the number of circulating leucocytes in humans. Fifty-nine patients undergoing elective surgery were anaesthetized with sevoflurane in oxygen. The inhaled concentration was increased gradually to 5% and maintained for 20 min. Arterial blood samples were obtained before induction of anaesthesia and at 20 min. While the total number of leucocytes remained constant, circulating neutrophils decreased (mean 3370 (SD 1030) mm-3 to 3170 (940) mm-3; P < 0.01) and lymphocytes increased (1870 (520) mm-3 to 2040 (580) mm-3; P < 0.01). We conclude that high concentrations of sevoflurane modified the distribution of leucocytes in anaesthetized patients.

Original languageEnglish
Pages (from-to)502-503
Number of pages2
JournalBritish Journal of Anaesthesia
Volume80
Issue number4
Publication statusPublished - 1998 Apr

Fingerprint

Leukocytes
Anesthesia
Leukocyte Count
Neutrophils
Lymphocytes
Oxygen
sevoflurane

Keywords

  • Anaesthetics volatile, sevoflurane
  • Blood, leucocytes
  • Blood, lymphocytes
  • Blood, neutrophils

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Morisaki, H., Aoyama, Y., Shimada, M., Ochiai, R., & Takeda, J. (1998). Leucocyte distribution during sevoflurane anaesthesia. British Journal of Anaesthesia, 80(4), 502-503.

Leucocyte distribution during sevoflurane anaesthesia. / Morisaki, Hiroshi; Aoyama, Y.; Shimada, M.; Ochiai, R.; Takeda, J.

In: British Journal of Anaesthesia, Vol. 80, No. 4, 04.1998, p. 502-503.

Research output: Contribution to journalArticle

Morisaki, H, Aoyama, Y, Shimada, M, Ochiai, R & Takeda, J 1998, 'Leucocyte distribution during sevoflurane anaesthesia', British Journal of Anaesthesia, vol. 80, no. 4, pp. 502-503.
Morisaki H, Aoyama Y, Shimada M, Ochiai R, Takeda J. Leucocyte distribution during sevoflurane anaesthesia. British Journal of Anaesthesia. 1998 Apr;80(4):502-503.
Morisaki, Hiroshi ; Aoyama, Y. ; Shimada, M. ; Ochiai, R. ; Takeda, J. / Leucocyte distribution during sevoflurane anaesthesia. In: British Journal of Anaesthesia. 1998 ; Vol. 80, No. 4. pp. 502-503.
@article{7ddc7b61ef4b427ca246938b2b0c2e6b,
title = "Leucocyte distribution during sevoflurane anaesthesia",
abstract = "We have examined if sevoflurane anaesthesia per se modified the number of circulating leucocytes in humans. Fifty-nine patients undergoing elective surgery were anaesthetized with sevoflurane in oxygen. The inhaled concentration was increased gradually to 5{\%} and maintained for 20 min. Arterial blood samples were obtained before induction of anaesthesia and at 20 min. While the total number of leucocytes remained constant, circulating neutrophils decreased (mean 3370 (SD 1030) mm-3 to 3170 (940) mm-3; P < 0.01) and lymphocytes increased (1870 (520) mm-3 to 2040 (580) mm-3; P < 0.01). We conclude that high concentrations of sevoflurane modified the distribution of leucocytes in anaesthetized patients.",
keywords = "Anaesthetics volatile, sevoflurane, Blood, leucocytes, Blood, lymphocytes, Blood, neutrophils",
author = "Hiroshi Morisaki and Y. Aoyama and M. Shimada and R. Ochiai and J. Takeda",
year = "1998",
month = "4",
language = "English",
volume = "80",
pages = "502--503",
journal = "British Journal of Anaesthesia",
issn = "0007-0912",
publisher = "Oxford University Press",
number = "4",

}

TY - JOUR

T1 - Leucocyte distribution during sevoflurane anaesthesia

AU - Morisaki, Hiroshi

AU - Aoyama, Y.

AU - Shimada, M.

AU - Ochiai, R.

AU - Takeda, J.

PY - 1998/4

Y1 - 1998/4

N2 - We have examined if sevoflurane anaesthesia per se modified the number of circulating leucocytes in humans. Fifty-nine patients undergoing elective surgery were anaesthetized with sevoflurane in oxygen. The inhaled concentration was increased gradually to 5% and maintained for 20 min. Arterial blood samples were obtained before induction of anaesthesia and at 20 min. While the total number of leucocytes remained constant, circulating neutrophils decreased (mean 3370 (SD 1030) mm-3 to 3170 (940) mm-3; P < 0.01) and lymphocytes increased (1870 (520) mm-3 to 2040 (580) mm-3; P < 0.01). We conclude that high concentrations of sevoflurane modified the distribution of leucocytes in anaesthetized patients.

AB - We have examined if sevoflurane anaesthesia per se modified the number of circulating leucocytes in humans. Fifty-nine patients undergoing elective surgery were anaesthetized with sevoflurane in oxygen. The inhaled concentration was increased gradually to 5% and maintained for 20 min. Arterial blood samples were obtained before induction of anaesthesia and at 20 min. While the total number of leucocytes remained constant, circulating neutrophils decreased (mean 3370 (SD 1030) mm-3 to 3170 (940) mm-3; P < 0.01) and lymphocytes increased (1870 (520) mm-3 to 2040 (580) mm-3; P < 0.01). We conclude that high concentrations of sevoflurane modified the distribution of leucocytes in anaesthetized patients.

KW - Anaesthetics volatile, sevoflurane

KW - Blood, leucocytes

KW - Blood, lymphocytes

KW - Blood, neutrophils

UR - http://www.scopus.com/inward/record.url?scp=0031917038&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031917038&partnerID=8YFLogxK

M3 - Article

C2 - 9640157

AN - SCOPUS:0031917038

VL - 80

SP - 502

EP - 503

JO - British Journal of Anaesthesia

JF - British Journal of Anaesthesia

SN - 0007-0912

IS - 4

ER -