Leucocyte distribution during sevoflurane anaesthesia

H. Morisaki; Y. Aoyama; M. Shimada; R. Ochiai; J. Takeda

doi:10.1093/bja/80.4.502

Leucocyte distribution during sevoflurane anaesthesia

H. Morisaki, Y. Aoyama, M. Shimada, R. Ochiai, J. Takeda

Department of Anesthesiology

Research output: Contribution to journal › Article › peer-review

25 Citations (Scopus)

Abstract

We have examined if sevoflurane anaesthesia per se modified the number of circulating leucocytes in humans. Fifty-nine patients undergoing elective surgery were anaesthetized with sevoflurane in oxygen. The inhaled concentration was increased gradually to 5% and maintained for 20 min. Arterial blood samples were obtained before induction of anaesthesia and at 20 min. While the total number of leucocytes remained constant, circulating neutrophils decreased (mean 3370 (SD 1030) mm^-3 to 3170 (940) mm^-3; P < 0.01) and lymphocytes increased (1870 (520) mm^-3 to 2040 (580) mm^-3; P < 0.01). We conclude that high concentrations of sevoflurane modified the distribution of leucocytes in anaesthetized patients.

Original language	English
Pages (from-to)	502-503
Number of pages	2
Journal	British Journal of Anaesthesia
Volume	80
Issue number	4
DOIs	https://doi.org/10.1093/bja/80.4.502
Publication status	Published - 1998 Apr

Keywords

Anaesthetics volatile, sevoflurane
Blood, leucocytes
Blood, lymphocytes
Blood, neutrophils

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1093/bja/80.4.502

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AU - Morisaki, H.

AU - Aoyama, Y.

AU - Shimada, M.

AU - Ochiai, R.

AU - Takeda, J.

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Leucocyte distribution during sevoflurane anaesthesia

Abstract

Keywords

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