[Limbic encephalitis up to date].

Morinobu Seki, Shigeaki Suzuki, Norihiro Suzuki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Limbic encephalitis (LE) refers to an inflammatory disorder involving the hippocampus, amygdala and insular cortex. LE is now regarded as a more frequent disorder than it was previously thought, and the concept of LE has been expanded because of the development of neuroimaging and the increasing recognition of the associated antibodies. We categorized LE into 5 groups. LE caused by virus infection, autoantibody-mediated LE, LE with autoimmune disease, LE associated with drugs and LE during pregnancy. LE having the antibodies against intracellular antigens frequently related to cancer and are resistant to treatment. While, LE with antibodies against cell-membrane antigens, including NMDAR, AMPAR, GABA(B)R, VGKC, tend to respond better to antitumor therapy and immunotherapy.

Original languageEnglish
Pages (from-to)442-447
Number of pages6
JournalNippon rinsho. Japanese journal of clinical medicine
Volume69
Issue number3
Publication statusPublished - 2011 Mar

Fingerprint

Limbic Encephalitis
Antibodies
Encephalitis Viruses
Antigens
Virus Diseases
Amygdala
Neuroimaging
Cerebral Cortex
Autoantibodies
Immunotherapy
gamma-Aminobutyric Acid
Autoimmune Diseases
Hippocampus

ASJC Scopus subject areas

  • Medicine(all)

Cite this

[Limbic encephalitis up to date]. / Seki, Morinobu; Suzuki, Shigeaki; Suzuki, Norihiro.

In: Nippon rinsho. Japanese journal of clinical medicine, Vol. 69, No. 3, 03.2011, p. 442-447.

Research output: Contribution to journalArticle

@article{eba7fb7817f0467bbbbdb49b750164ef,
title = "[Limbic encephalitis up to date].",
abstract = "Limbic encephalitis (LE) refers to an inflammatory disorder involving the hippocampus, amygdala and insular cortex. LE is now regarded as a more frequent disorder than it was previously thought, and the concept of LE has been expanded because of the development of neuroimaging and the increasing recognition of the associated antibodies. We categorized LE into 5 groups. LE caused by virus infection, autoantibody-mediated LE, LE with autoimmune disease, LE associated with drugs and LE during pregnancy. LE having the antibodies against intracellular antigens frequently related to cancer and are resistant to treatment. While, LE with antibodies against cell-membrane antigens, including NMDAR, AMPAR, GABA(B)R, VGKC, tend to respond better to antitumor therapy and immunotherapy.",
author = "Morinobu Seki and Shigeaki Suzuki and Norihiro Suzuki",
year = "2011",
month = "3",
language = "English",
volume = "69",
pages = "442--447",
journal = "Nihon rinsho. Japanese journal of clinical medicine",
issn = "0047-1852",
publisher = "Nipponrinsho Co., Inc.",
number = "3",

}

TY - JOUR

T1 - [Limbic encephalitis up to date].

AU - Seki, Morinobu

AU - Suzuki, Shigeaki

AU - Suzuki, Norihiro

PY - 2011/3

Y1 - 2011/3

N2 - Limbic encephalitis (LE) refers to an inflammatory disorder involving the hippocampus, amygdala and insular cortex. LE is now regarded as a more frequent disorder than it was previously thought, and the concept of LE has been expanded because of the development of neuroimaging and the increasing recognition of the associated antibodies. We categorized LE into 5 groups. LE caused by virus infection, autoantibody-mediated LE, LE with autoimmune disease, LE associated with drugs and LE during pregnancy. LE having the antibodies against intracellular antigens frequently related to cancer and are resistant to treatment. While, LE with antibodies against cell-membrane antigens, including NMDAR, AMPAR, GABA(B)R, VGKC, tend to respond better to antitumor therapy and immunotherapy.

AB - Limbic encephalitis (LE) refers to an inflammatory disorder involving the hippocampus, amygdala and insular cortex. LE is now regarded as a more frequent disorder than it was previously thought, and the concept of LE has been expanded because of the development of neuroimaging and the increasing recognition of the associated antibodies. We categorized LE into 5 groups. LE caused by virus infection, autoantibody-mediated LE, LE with autoimmune disease, LE associated with drugs and LE during pregnancy. LE having the antibodies against intracellular antigens frequently related to cancer and are resistant to treatment. While, LE with antibodies against cell-membrane antigens, including NMDAR, AMPAR, GABA(B)R, VGKC, tend to respond better to antitumor therapy and immunotherapy.

UR - http://www.scopus.com/inward/record.url?scp=79955664246&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79955664246&partnerID=8YFLogxK

M3 - Article

VL - 69

SP - 442

EP - 447

JO - Nihon rinsho. Japanese journal of clinical medicine

JF - Nihon rinsho. Japanese journal of clinical medicine

SN - 0047-1852

IS - 3

ER -