Linkage Analysis of Affective Disorder Using DNA Markers on Chromosomes 11 and X

Shinichiro Nanko, Masaru Kobayashi, Shinobu Gamou, Jun Kudo, Nobuyoshi Shimizu, Noboru Takazawa, Hajime Kazamatsuri, Toshiyuki Furusho

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Abstract: We have investigated two pedigrees in an attempt to detect the putative linkages between affective disorder and c‐Ha‐ras‐1 oncogene and the insulin gene on chromosome 11, or hypoxanthhte phosphoribosyltransferase (HPRT) on X chromosome. The linkage between affective disorders and the markers on chromosomes 11 and X was ruled out with the assumption of no recombination.

Original languageEnglish
Pages (from-to)53-56
Number of pages4
JournalPsychiatry and Clinical Neurosciences
Volume45
Issue number1
DOIs
Publication statusPublished - 1991 Jan 1

Fingerprint

Chromosomes, Human, Pair 11
Mood Disorders
Genetic Markers
X Chromosome
Pedigree
Oncogenes
Genetic Recombination
Insulin
Genes

Keywords

  • affective disorder
  • DNA markers
  • linkage
  • RFLP

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Nanko, S., Kobayashi, M., Gamou, S., Kudo, J., Shimizu, N., Takazawa, N., ... Furusho, T. (1991). Linkage Analysis of Affective Disorder Using DNA Markers on Chromosomes 11 and X. Psychiatry and Clinical Neurosciences, 45(1), 53-56. https://doi.org/10.1111/j.1440-1819.1991.tb00505.x

Linkage Analysis of Affective Disorder Using DNA Markers on Chromosomes 11 and X. / Nanko, Shinichiro; Kobayashi, Masaru; Gamou, Shinobu; Kudo, Jun; Shimizu, Nobuyoshi; Takazawa, Noboru; Kazamatsuri, Hajime; Furusho, Toshiyuki.

In: Psychiatry and Clinical Neurosciences, Vol. 45, No. 1, 01.01.1991, p. 53-56.

Research output: Contribution to journalArticle

Nanko, S, Kobayashi, M, Gamou, S, Kudo, J, Shimizu, N, Takazawa, N, Kazamatsuri, H & Furusho, T 1991, 'Linkage Analysis of Affective Disorder Using DNA Markers on Chromosomes 11 and X', Psychiatry and Clinical Neurosciences, vol. 45, no. 1, pp. 53-56. https://doi.org/10.1111/j.1440-1819.1991.tb00505.x
Nanko, Shinichiro ; Kobayashi, Masaru ; Gamou, Shinobu ; Kudo, Jun ; Shimizu, Nobuyoshi ; Takazawa, Noboru ; Kazamatsuri, Hajime ; Furusho, Toshiyuki. / Linkage Analysis of Affective Disorder Using DNA Markers on Chromosomes 11 and X. In: Psychiatry and Clinical Neurosciences. 1991 ; Vol. 45, No. 1. pp. 53-56.
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