Lipid Conjugates as Ligands for the C-type Lectin Receptor Mincle

Research output: Contribution to journalShort surveypeer-review

Abstract

C-type lectin receptors (CLRs), a class of pattern recognition receptors, are expressed on immune cell surfaces and regulate innate immunity by recognizing microbial or endogenous substances. Mincle, a CLR, recognizes various lipid conjugated ligands, such as glycolipids. In this review, recently synthetically accessed natural Mincle ligand-lipid conjugates as well as their analogues are discussed.

Original languageEnglish
Pages (from-to)E55-E59
JournalTrends in Glycoscience and Glycotechnology
Volume34
Issue number199
DOIs
Publication statusPublished - 2022

Keywords

  • C-type lectin receptor
  • glycolipids
  • innate immunity
  • lipid conjugates
  • Mincle

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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