Abstract
It′s all about the timing: Precise control of the residence time (t Rx; see picture) of reactive intermediates in flow microreactors enables the reaction pathway of lithiated 1,2-dichloroethene to be switched to produce either alkenes or alkynes. This method also allows versatile syntheses of asymmetric disubstituted dichloroalkenes and alkynes.
Original language | English |
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Pages (from-to) | 3245-3248 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 51 |
Issue number | 13 |
DOIs | |
Publication status | Published - 2012 Mar 26 |
Externally published | Yes |
Keywords
- alkenes
- alkynes
- lithiation
- microreactors
- synthetic methods
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)