Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter-→q15

S. Minoshima, M. Amagai, J. Kudoh, R. Fukuyama, T. Hashimoto, T. Nishikawa, N. Shimizu

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Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p-(6pter-→q15::16q24-→qter). The gene (BPA230) was located to the chromosome region 6pter-→q 15.

Original languageEnglish
Pages (from-to)30-32
Number of pages3
JournalCytogenetic and Genome Research
Issue number1
Publication statusPublished - 1991 Jan 1


ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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