Locally delivered minocycline and guided tissue regeneration to treat post-juvenile periodontitis. A case report.

A. Saito, Y. Hosaka, T. Nakagawa, K. Seida, S. Yamada, K. Okuda

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A case of post-juvenile periodontitis in a 28-year-old female patient is described along with new periodontal treatment modalities. Administration of minocycline-HCl with local drug delivery system was introduced as a part of initial periodontal therapy following microbiological and immunological examinations. The lesions were subsequently treated by guided tissue regeneration, which resulted in considerable gain of attachment with minimal recession of marginal gingiva. This observation suggests that the local delivery of antibiotics and regenerative therapy may prove to be effective alternative modalities in treatment of post-juvenile periodontitis.

Original languageEnglish
Pages (from-to)835-839
Number of pages5
JournalJournal of Periodontology
Issue number9
Publication statusPublished - 1994 Jan 1
Externally publishedYes



  • guided tissue regeneration
  • juvenile/drug therapy
  • minocycline/therapeutic use
  • periodontitis

ASJC Scopus subject areas

  • Periodontics

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