Locational analysis of glutathione in liposomes by using small-angle X-ray scattering

Mina Sakuragi; Takuya Zushi; Risako Seguchi; Taishi Arai; Kazuaki Taguchi; Katsuki Kusakabe

doi:10.1246/cl.160932

Locational analysis of glutathione in liposomes by using small-angle X-ray scattering

Mina Sakuragi, Takuya Zushi, Risako Seguchi, Taishi Arai, Kazuaki Taguchi, Katsuki Kusakabe

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

We investigated the effect of the surface charge and volume of the aqueous phase ofliposomes on the antioxidant glutathione (GSH) entrapment ratio in liposomes. The entrapment ratio increased by decreasing the molar ratio of the cationic lipid. Furthermore, we investigated in detail the location of the GSH in liposomes with SAXS data using the Fourier transformation method.

Original language	English
Pages (from-to)	185-187
Number of pages	3
Journal	Chemistry Letters
Volume	46
Issue number	2
DOIs	https://doi.org/10.1246/cl.160932
Publication status	Published - 2017 Jan 1
Externally published	Yes

Keywords

Glutathione
Liposome
Small-angle X-ray scattering (SAXS)

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.160932

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keywords = "Glutathione, Liposome, Small-angle X-ray scattering (SAXS)",

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AU - Sakuragi, Mina

AU - Zushi, Takuya

AU - Seguchi, Risako

AU - Arai, Taishi

AU - Taguchi, Kazuaki

AU - Kusakabe, Katsuki

PY - 2017/1/1

Y1 - 2017/1/1

N2 - We investigated the effect of the surface charge and volume of the aqueous phase ofliposomes on the antioxidant glutathione (GSH) entrapment ratio in liposomes. The entrapment ratio increased by decreasing the molar ratio of the cationic lipid. Furthermore, we investigated in detail the location of the GSH in liposomes with SAXS data using the Fourier transformation method.

AB - We investigated the effect of the surface charge and volume of the aqueous phase ofliposomes on the antioxidant glutathione (GSH) entrapment ratio in liposomes. The entrapment ratio increased by decreasing the molar ratio of the cationic lipid. Furthermore, we investigated in detail the location of the GSH in liposomes with SAXS data using the Fourier transformation method.

KW - Glutathione

KW - Liposome

KW - Small-angle X-ray scattering (SAXS)

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ER -

Locational analysis of glutathione in liposomes by using small-angle X-ray scattering

Abstract

Keywords

ASJC Scopus subject areas

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