Long-Term Outcome of Patients with Locally Resected High- and Low-Risk Rectal Carcinoid Tumors

Kohei Shigeta, Koji Okabayashi, Hirotoshi Hasegawa, Yoshiyuki Ishii, Hiroki Ochiai, Masashi Tsuruta, Makio Mukai, Kaori Kameyama, Toshio Uraoka, Naohisa Yahagi, Yuukou Kitagawa

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: Tumor size and lymphovascular invasion are known high-risk factors for lymph node and distant metastasis in patients with rectal carcinoid tumors. However, the optimal treatment for these tumors remains controversial. Aim: The aim of this paper is to compare the outcome of local or radical resection between patients with high-risk (tumor size >10 mm or lymphovascular invasion) disease and those with low-risk (tumor size ≤10 mm, no lymphovascular invasion) disease. Methods: Patients with rectal carcinoid tumors treated between January 1990 and March 2010 were identified retrospectively and classified into low- and high-risk groups. Results: In total, 83 patients with rectal carcinoid tumors were included, 53 (64 %) of whom were identified as low-risk and 30 (36 %) as high-risk. Local resection was performed in 50 (60 %) low-risk and 24 (29 %) high-risk patients, and postoperative recurrence was observed in one (1 %) of the high-risk patients who underwent local resection and one (11 %) who underwent radical resection. No recurrence was observed in the low-risk group. Kaplan-Meier analysis of the patients who underwent local resection revealed that the 10-year disease-free survival rate was 100 % in the low-risk group and 83.3 % in the high-risk group. Conclusions: There was no significant difference in outcome between local and radical resection.

Original languageEnglish
Pages (from-to)768-773
Number of pages6
JournalJournal of Gastrointestinal Surgery
Volume18
Issue number4
DOIs
Publication statusPublished - 2014

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Carcinoid Tumor
Rectal Neoplasms
Neoplasms
Recurrence
Kaplan-Meier Estimate
Disease-Free Survival
Survival Rate
Lymph Nodes
Neoplasm Metastasis

Keywords

  • Local resection
  • Rectal carcinoid tumors
  • Survival outcome

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

Cite this

Long-Term Outcome of Patients with Locally Resected High- and Low-Risk Rectal Carcinoid Tumors. / Shigeta, Kohei; Okabayashi, Koji; Hasegawa, Hirotoshi; Ishii, Yoshiyuki; Ochiai, Hiroki; Tsuruta, Masashi; Mukai, Makio; Kameyama, Kaori; Uraoka, Toshio; Yahagi, Naohisa; Kitagawa, Yuukou.

In: Journal of Gastrointestinal Surgery, Vol. 18, No. 4, 2014, p. 768-773.

Research output: Contribution to journalArticle

Shigeta, Kohei ; Okabayashi, Koji ; Hasegawa, Hirotoshi ; Ishii, Yoshiyuki ; Ochiai, Hiroki ; Tsuruta, Masashi ; Mukai, Makio ; Kameyama, Kaori ; Uraoka, Toshio ; Yahagi, Naohisa ; Kitagawa, Yuukou. / Long-Term Outcome of Patients with Locally Resected High- and Low-Risk Rectal Carcinoid Tumors. In: Journal of Gastrointestinal Surgery. 2014 ; Vol. 18, No. 4. pp. 768-773.
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AU - Ishii, Yoshiyuki

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