Long-Term Outcomes of Percutaneous Radiofrequency Thermocoagulation of Gasserian Ganglion for 2nd- and Multiple-Division Trigeminal Neuralgia

Shizuko Kosugi, Masahiro Shiotani, Yasuhisa Otsuka, Takeshi Suzuki, Nobuyuki Katori, Saori Hashiguchi, Hiroshi Morisaki

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Objectives: The objective of this study was to examine the long-term outcome of percutaneous radiofrequency thermocoagulation (PRT) of the Gasserian ganglion for the 2nd division and multiple division trigeminal neuralgia (TN), compared to the isolated 3rd division TN. Methods: One hundred and forty-eight procedures performed in 89 patients with typical TN between April 2004 and September 2011 in a single pain center were retrospectively analyzed. Baseline characteristics of these patients, immediate outcome, duration pain-free, and complications were obtained from their medical records and questionnaires sent in June 2012. Duration pain-free was assessed by Kaplan-Meier analysis. Results: Of the 148 PRT of the Gasserian ganglion, 37 procedures were performed for isolated 2nd-division TN (V2 TN), 67 procedures were for both 2nd- and 3rd-division TN (V2 + V3 TN), and 38 procedures were for isolated 3rd-division TN (V3 TN). The remaining 6 procedures were performed for V1 + V2 TN and V1 + V2 + V3 TN. Immediate success rates of PRT for V2 TN, V2 + V3 TN, and V3 TN were 100%, 86.6%, and 100%, respectively, whereas the durations pain-free for V2 TN and V2 + V3 TN were significantly shorter than that for V3 TN (9, 12, and 36 months, respectively: P = 0.012). Conclusion: For 2nd-division TN and multiple-division TN, less long-term pain relief after PRT of the Gasserian ganglion can be expected compared with that for isolated trigeminal 3rd-division neuralgia, even if immediate pain relief is achieved.

Original languageEnglish
Pages (from-to)223-228
Number of pages6
JournalPain Practice
Issue number3
Publication statusPublished - 2015 Mar 1



  • Gasserian ganglion
  • Outcomes
  • Radiofrequency ablation
  • Trigeminal neuralgia
  • Trigeminal neuralgia, idiopathic

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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