A 56-year-old man with advanced gastric tumor in the pyloric antrum had multiple lymph node metastases (lymph nodes #5, 6, 8, and 13), as revealed by abdominal computed tomography (CT). The patient was diagnosed with coexisting clinical Stage IIIA gastric cancer (cT2 [SS], cN2, cMO) with concomitant malignant lymphoma. Distal gastrectomy, D2 lymph node dissection, and resection of lymph node 3 were performed. Histopathological findings indicated that both the primary tumor and lymph node metastases were neuroendocrine carcinomas. Adjuvant chemotherapy with S-1 was administered; however, follow-up CT after 6 months revealed local recurrence around the celiac artery. Therefore, the chemotherapy regimen was changed to irinotecan and cisplatin. A clinical complete response was obtained after 6 chemotherapy courses and maintained for up to 45 months. The patient is alive at 60 months after the operation.
|Number of pages||4|
|Journal||Japanese Journal of Cancer and Chemotherapy|
|Publication status||Published - 2017 Apr|
- Gastric neuroendocrine cell carcinoma
ASJC Scopus subject areas
- Cancer Research