Long-term survival of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement

Tomotaka Akatsu, Motohide Shimazu, Shigeyuki Kawachi, Minoru Tanabe, Koichi Aiura, Go Wakabashi, Masakazu Ueda, Michiie Sakamoto, Masaki Kitajima

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

We report the case of a very rare 6-year disease-free survivor of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement. A 76-year-old female with liver dysfunction was referred to our institution. Contrast-enhanced computed tomography showed a 5-cm low-density tumor with irregular marginal enhancement in the left and caudate lobes of the liver. Cholangiography revealed complete obstruction of the left hepatic bile duct. Angiography showed obstruction of the left branch of the portal vein. Metastasis to the hilar lymph nodes was disclosed at surgery. The patient underwent left hepatectomy with caudate lobectomy, resection of the extrahepatic bile duct, and lymphadenectomy. The total vascular exclusion of the liver was used for hepatectomy and reconstruction of the portal vein. Microscopically, the tumor was a poorly differentiated adenocarcinoma with many infiltrating lymphocytes, and extensive necrosis was present within the tumor. The experience gained in the present case suggests that aggressive surgery may be a potential approach to provide a hope of long-term survival for patients with intrahepatic cholangiocarcinoma despite the presence of regional lymph node metastasis and vascular invasion.

Original languageEnglish
Pages (from-to)603-605
Number of pages3
JournalHepato-Gastroenterology
Volume52
Issue number62
Publication statusPublished - 2005 Mar

Fingerprint

Cholangiocarcinoma
Portal Vein
Lymph Nodes
Hepatectomy
Neoplasm Metastasis
Blood Vessels
Survival
Extrahepatic Bile Ducts
Common Hepatic Duct
Neoplasms
Cholangiography
Liver
Bile Ducts
Lymph Node Excision
Survivors
Liver Diseases
Angiography
Adenocarcinoma
Necrosis
Tomography

Keywords

  • Aggressive surgery
  • Intrahepatic cholangiocarcinoma
  • Long-term survival
  • Lymph node metastasis
  • Portal vein involvement

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Akatsu, T., Shimazu, M., Kawachi, S., Tanabe, M., Aiura, K., Wakabashi, G., ... Kitajima, M. (2005). Long-term survival of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement. Hepato-Gastroenterology, 52(62), 603-605.

Long-term survival of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement. / Akatsu, Tomotaka; Shimazu, Motohide; Kawachi, Shigeyuki; Tanabe, Minoru; Aiura, Koichi; Wakabashi, Go; Ueda, Masakazu; Sakamoto, Michiie; Kitajima, Masaki.

In: Hepato-Gastroenterology, Vol. 52, No. 62, 03.2005, p. 603-605.

Research output: Contribution to journalArticle

Akatsu, T, Shimazu, M, Kawachi, S, Tanabe, M, Aiura, K, Wakabashi, G, Ueda, M, Sakamoto, M & Kitajima, M 2005, 'Long-term survival of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement', Hepato-Gastroenterology, vol. 52, no. 62, pp. 603-605.
Akatsu T, Shimazu M, Kawachi S, Tanabe M, Aiura K, Wakabashi G et al. Long-term survival of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement. Hepato-Gastroenterology. 2005 Mar;52(62):603-605.
Akatsu, Tomotaka ; Shimazu, Motohide ; Kawachi, Shigeyuki ; Tanabe, Minoru ; Aiura, Koichi ; Wakabashi, Go ; Ueda, Masakazu ; Sakamoto, Michiie ; Kitajima, Masaki. / Long-term survival of intrahepatic cholangiocarcinoma with hilar lymph node metastasis and portal vein involvement. In: Hepato-Gastroenterology. 2005 ; Vol. 52, No. 62. pp. 603-605.
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