Longitudinal follow-up of pulmonary function after lobectomy in childhood - Factors affecting lung growth

C. Nakajima, C. Kijimoto, Y. Yokoyama, T. Miyakawa, Y. Tsuchiya, Tatsuo Kuroda, M. Nakano, M. Saeki

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Abstract

We examined the changes in pulmonary function values in 27 patients who underwent a lobectomy due to cystic lung disease and compared the results regarding such factors as disease type, age at operation, and preoperative infections. Percent vital capacity (%VC) decreased immediately after lobectomy, but recovered to normal values within 2 postoperative years and remained within or above the normal range. The ratio of residual volume to total lung capacity (RV/TLC) rose temporally with the increase in %VC, but then remained normal after 2 postoperative years. There was no difference in %VC and RV/TLC between diseases, while bronchial atresia showed a significantly lower correlation with percent of forced expiratory volume at 1 s. The older group operated upon at over 4 years of age and the group that had infections before operation showed relatively low %VC and high RV/TLC. Some patients demonstrated extremely low %VC along with funnel chest deformities. Our study suggests that overinflation of the remaining lung compensates VC in the early period after lobectomy while subsequently alveolar multiplication occurs. Factors affecting compensatory lung growth were considered to be operation later than 4 years of age, preoperative infection, and a thoracic deformity.

Original languageEnglish
Pages (from-to)341-345
Number of pages5
JournalPediatric Surgery International
Volume13
Issue number5-6
DOIs
Publication statusPublished - 1998 Jul
Externally publishedYes

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Keywords

  • Childhood
  • Lobectomy
  • Pulmonary function

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Nakajima, C., Kijimoto, C., Yokoyama, Y., Miyakawa, T., Tsuchiya, Y., Kuroda, T., Nakano, M., & Saeki, M. (1998). Longitudinal follow-up of pulmonary function after lobectomy in childhood - Factors affecting lung growth. Pediatric Surgery International, 13(5-6), 341-345. https://doi.org/10.1007/s003830050334