Lyngbyacyclamides A and B, novel cytotoxic peptides from marine cyanobacteria Lyngbya sp.

Norihito Maru; Osamu Ohno; Daisuke Uemura

doi:10.1016/j.tetlet.2010.06.105

Lyngbyacyclamides A and B, novel cytotoxic peptides from marine cyanobacteria Lyngbya sp.

Norihito Maru, Osamu Ohno, Daisuke Uemura

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Lyngbyacyclamides A (1) and B (2), novel cyclic peptides, were isolated from marine cyanobacteria Lyngbya sp. collected in Okinawa, Japan. Their structures were determined by spectroscopic analyses and degradation studies. They moderately inhibited the growth of B16 mouse melanoma cells.

Original language	English
Pages (from-to)	6384-6387
Number of pages	4
Journal	Tetrahedron Letters
Volume	51
Issue number	49
DOIs	https://doi.org/10.1016/j.tetlet.2010.06.105
Publication status	Published - 2010 Dec 8

Keywords

Cyclic peptide
Cytotoxicity
Lyngbya sp.
Lyngbyacyclamide A

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2010.06.105

Fingerprint Dive into the research topics of 'Lyngbyacyclamides A and B, novel cytotoxic peptides from marine cyanobacteria Lyngbya sp.'. Together they form a unique fingerprint.

Cite this

@article{dda980675e6a4c1ea64f2812f4756c1e,

title = "Lyngbyacyclamides A and B, novel cytotoxic peptides from marine cyanobacteria Lyngbya sp.",

abstract = "Lyngbyacyclamides A (1) and B (2), novel cyclic peptides, were isolated from marine cyanobacteria Lyngbya sp. collected in Okinawa, Japan. Their structures were determined by spectroscopic analyses and degradation studies. They moderately inhibited the growth of B16 mouse melanoma cells.",

keywords = "Cyclic peptide, Cytotoxicity, Lyngbya sp., Lyngbyacyclamide A",

author = "Norihito Maru and Osamu Ohno and Daisuke Uemura",

note = "Funding Information: This work was supported in part by JSPS via Grants-in-Aid for Scientific Research ( 16GS0206 , 21221009 , and 20611006 ) and the Global-COE program in Chemistry, Nagoya University. ",

year = "2010",

month = dec,

day = "8",

doi = "10.1016/j.tetlet.2010.06.105",

language = "English",

volume = "51",

pages = "6384--6387",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "49",

}

TY - JOUR

T1 - Lyngbyacyclamides A and B, novel cytotoxic peptides from marine cyanobacteria Lyngbya sp.

AU - Maru, Norihito

AU - Ohno, Osamu

AU - Uemura, Daisuke

N1 - Funding Information: This work was supported in part by JSPS via Grants-in-Aid for Scientific Research ( 16GS0206 , 21221009 , and 20611006 ) and the Global-COE program in Chemistry, Nagoya University.

PY - 2010/12/8

Y1 - 2010/12/8

N2 - Lyngbyacyclamides A (1) and B (2), novel cyclic peptides, were isolated from marine cyanobacteria Lyngbya sp. collected in Okinawa, Japan. Their structures were determined by spectroscopic analyses and degradation studies. They moderately inhibited the growth of B16 mouse melanoma cells.

AB - Lyngbyacyclamides A (1) and B (2), novel cyclic peptides, were isolated from marine cyanobacteria Lyngbya sp. collected in Okinawa, Japan. Their structures were determined by spectroscopic analyses and degradation studies. They moderately inhibited the growth of B16 mouse melanoma cells.

KW - Cyclic peptide

KW - Cytotoxicity

KW - Lyngbya sp.

KW - Lyngbyacyclamide A

UR - http://www.scopus.com/inward/record.url?scp=78149285175&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78149285175&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2010.06.105

DO - 10.1016/j.tetlet.2010.06.105

M3 - Article

AN - SCOPUS:78149285175

VL - 51

SP - 6384

EP - 6387

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 49

ER -