[Macrolide-resistant Mycoplasma pneumoniae].

Miyuki Morozumi, Kimiko Ubukata

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Mycoplasma pneumoniae (M. pn) is one of the main pathogens causing community-acquired pneumonia (CAP) in children. In Japan, macrolide (ML)-resistant M. pn was firstly isolated from clinical samples collected from pediatric patients with CAP in 2000, and the agents have rapidly increased. All ML-resistant strains had a point mutation in domain V of the 23S rRNA. Among the patients with ML-resistant M. pn, the duration of fever was significantly longer than in patients with ML-susceptible M. pn infection. The antimicrobial agent was often changed from ML as a first choice agent to minocycline or levofloxacin, because of unimproved clinical symptoms. Further clinical studies are needed to establish appropriate chemotherapy.

Original languageEnglish
Pages (from-to)251-255
Number of pages5
JournalNihon rinsho. Japanese journal of clinical medicine
Volume70
Issue number2
Publication statusPublished - 2012 Feb
Externally publishedYes

Fingerprint

Mycoplasma pneumoniae
Macrolides
Pneumonia
Levofloxacin
Minocycline
Anti-Infective Agents
Point Mutation
Japan
Fever
Pediatrics
Drug Therapy
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

[Macrolide-resistant Mycoplasma pneumoniae]. / Morozumi, Miyuki; Ubukata, Kimiko.

In: Nihon rinsho. Japanese journal of clinical medicine, Vol. 70, No. 2, 02.2012, p. 251-255.

Research output: Contribution to journalArticle

Morozumi, M & Ubukata, K 2012, '[Macrolide-resistant Mycoplasma pneumoniae].', Nihon rinsho. Japanese journal of clinical medicine, vol. 70, no. 2, pp. 251-255.
Morozumi, Miyuki ; Ubukata, Kimiko. / [Macrolide-resistant Mycoplasma pneumoniae]. In: Nihon rinsho. Japanese journal of clinical medicine. 2012 ; Vol. 70, No. 2. pp. 251-255.
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