Magnetophoresis for mononuclear cell separation and diagnostic evaluation of the phagocytic capacity of monocyte

Haruyuki Minamitani, Takuji Shimomura, Masayuki Aiba, Eiji Okada

Research output: Contribution to conferencePaper

Abstract

The authors discuss magnetophoresis, which specifically separates monocytes phagocytizing iron dextran microspheres from mononuclear cell suspensions under a DC magnetic field. Diagnostic evaluation of the phagocytic capacity was carried out for patients with liver diseases on the basis of the separation efficiency of the monocytes. Results of the magnetic separation showed that the phagocytic capacities of hepatoma and liver cirrhosis became significantly lower than those of healthy volunteers, and that the magnetophoresis was essentially available to investigate the phagocytosis.

Original languageEnglish
Pages1328-1330
Number of pages3
DOIs
Publication statusPublished - 1988
EventProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society - New Orleans, LA, USA
Duration: 1988 Nov 41988 Nov 7

Other

OtherProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityNew Orleans, LA, USA
Period88/11/488/11/7

ASJC Scopus subject areas

  • Engineering(all)

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    Minamitani, H., Shimomura, T., Aiba, M., & Okada, E. (1988). Magnetophoresis for mononuclear cell separation and diagnostic evaluation of the phagocytic capacity of monocyte. 1328-1330. Paper presented at Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, New Orleans, LA, USA, . https://doi.org/10.1109/iembs.1988.95127