Mal-function of TLRs by SOCS

Takashi Kobayashi, Giichi Takaesu, Akihiko Yoshimura

Research output: Contribution to journalComment/debate

19 Citations (Scopus)

Abstract

Suppressor of cytokine signaling 1 has been linked to the negative regulation of Toll-like receptor signaling. The mechanism for this seems to be suppressor of cytokine signaling 1-mediated degradation of the adaptor Mal, which is required for Toll-like receptor signaling.

Original languageEnglish
Pages (from-to)123-124
Number of pages2
JournalNature Immunology
Volume7
Issue number2
DOIs
Publication statusPublished - 2006 Feb 1
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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