Malignant Hypertension in a Patient with Primary Aldosteronism with Elevated Active Renin Concentration

Kiyoshi Oka, Koichi Hayashi, Tomonori Nakazato, Taichi Suzawa, Keiji Fujiwara, Takao Saruta

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A 40-year-old male, with a past history of hypertension but receiving no medical treatment, was referred. He manifested malignant hypertension (190/130 mmHg; Keith-Wagener III), renal dysfunction (serum creatinine, 3.8 mg/dl), and elevated plasma aldosterone (450 pg/ml) and active renin concentration (ARC, 104 pg/ml). His blood pressure was controlled with multiple antihypertensive agents and ARC thus decreased (4.3 pg/ml), but aldosterone remained elevated. Abdominal magnetic resonance imaging (MRI) revealed a right adrenal adenoma, and aldosterone-producing adenoma was confirmed by adrenal venous sampling. Primary aldosteronism very rarely develops to malignant hypertension, and even in that case ARC is suppressed. Therefore this is a rare case of primary aldosteronism complicated with malignant hypertension and high ARC.

Original languageEnglish
Pages (from-to)700-704
Number of pages5
JournalInternal Medicine
Volume36
Issue number10
Publication statusPublished - 1997

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Malignant Hypertension
AIDS-Related Complex
Hyperaldosteronism
Renin
Aldosterone
Adenoma
Antihypertensive Agents
Creatinine
Magnetic Resonance Imaging
Blood Pressure
Hypertension
Kidney
Serum

Keywords

  • Adrenal adenoma
  • Aldosterone
  • Hemolytic anemia
  • Hypertension
  • Renal injury
  • Renin

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Oka, K., Hayashi, K., Nakazato, T., Suzawa, T., Fujiwara, K., & Saruta, T. (1997). Malignant Hypertension in a Patient with Primary Aldosteronism with Elevated Active Renin Concentration. Internal Medicine, 36(10), 700-704.

Malignant Hypertension in a Patient with Primary Aldosteronism with Elevated Active Renin Concentration. / Oka, Kiyoshi; Hayashi, Koichi; Nakazato, Tomonori; Suzawa, Taichi; Fujiwara, Keiji; Saruta, Takao.

In: Internal Medicine, Vol. 36, No. 10, 1997, p. 700-704.

Research output: Contribution to journalArticle

Oka, K, Hayashi, K, Nakazato, T, Suzawa, T, Fujiwara, K & Saruta, T 1997, 'Malignant Hypertension in a Patient with Primary Aldosteronism with Elevated Active Renin Concentration', Internal Medicine, vol. 36, no. 10, pp. 700-704.
Oka K, Hayashi K, Nakazato T, Suzawa T, Fujiwara K, Saruta T. Malignant Hypertension in a Patient with Primary Aldosteronism with Elevated Active Renin Concentration. Internal Medicine. 1997;36(10):700-704.
Oka, Kiyoshi ; Hayashi, Koichi ; Nakazato, Tomonori ; Suzawa, Taichi ; Fujiwara, Keiji ; Saruta, Takao. / Malignant Hypertension in a Patient with Primary Aldosteronism with Elevated Active Renin Concentration. In: Internal Medicine. 1997 ; Vol. 36, No. 10. pp. 700-704.
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