We found that epicatechin gallate, a constituent of an extract of tea leaves (green tea) markedly lowered the minimum inhibitory concentration (MIC) of oxacillin and other β-lactams, but not of other antibacterial agents tested, in strains of methicillin-resistant Staphylococcus aureus. The antibacterial action of epicatechin gallate plus oxacillin was a bactericidal one.
- Epicatechin gallate
- Methicillin-resistant Staphylococcus aureus (MRSA)
- Minimum inhibitory concentration (MIC) reduction
ASJC Scopus subject areas
- Pharmaceutical Science