Massive bilateral vitreoretinal hemorrhage in patient with chronic refractory idiopathic thrombocytopenic purpura

Amy Okuda, Makoto Inoue, Kei Shinoda, Kazuo Tsubota

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Background: We describe a patient with chronic, refractory idiopathic thrombocytopenic purpura (ITP) who developed massive vitreoretinal hemorrhages in both eyes. Methods: A 49-year-old woman complained of an acute decrease of vision, and ophthalmoscopy revealed bilateral preretinal and subretinal hemorrhages around the optic disc. Her platelet counts were less than 5000/μl in spite of repetitive administration of corticosteroids and immunoglobulins with splenectomy for the chronic refractory ITP. One month later, she developed massive vitreoretinal hemorrhages bilaterally, and vision decreased to hand-motion. Results: Vitrectomy was performed on both eyes after medical treatment to increase platelet counts. The intraretinal hemorrhages were absorbed from the area around the disc and vision recovered to 20/100 in the right eye and 20/2000 in the left after one month. Conclusion: Massive vitreoretinal hemorrhages can develop in patients with chronic refractory ITP, and vitrectomy can be beneficial for this condition.

Original languageEnglish
Pages (from-to)1190-1193
Number of pages4
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume243
Issue number11
DOIs
Publication statusPublished - 2005 Nov

Fingerprint

Idiopathic Thrombocytopenic Purpura
Hemorrhage
Vitrectomy
Platelet Count
Ophthalmoscopy
Optic Disk
Splenectomy
Immunoglobulins
Adrenal Cortex Hormones
Hand

Keywords

  • Idiopatic thrombocytopenic purpura
  • Subretinal hemorrhage
  • Thrombocytopenia
  • Vitrectomy
  • Vitreous hemorrhage

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Massive bilateral vitreoretinal hemorrhage in patient with chronic refractory idiopathic thrombocytopenic purpura. / Okuda, Amy; Inoue, Makoto; Shinoda, Kei; Tsubota, Kazuo.

In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 243, No. 11, 11.2005, p. 1190-1193.

Research output: Contribution to journalArticle

@article{83dc72b0e1b64aa6a3c0bf32f2ebd11b,
title = "Massive bilateral vitreoretinal hemorrhage in patient with chronic refractory idiopathic thrombocytopenic purpura",
abstract = "Background: We describe a patient with chronic, refractory idiopathic thrombocytopenic purpura (ITP) who developed massive vitreoretinal hemorrhages in both eyes. Methods: A 49-year-old woman complained of an acute decrease of vision, and ophthalmoscopy revealed bilateral preretinal and subretinal hemorrhages around the optic disc. Her platelet counts were less than 5000/μl in spite of repetitive administration of corticosteroids and immunoglobulins with splenectomy for the chronic refractory ITP. One month later, she developed massive vitreoretinal hemorrhages bilaterally, and vision decreased to hand-motion. Results: Vitrectomy was performed on both eyes after medical treatment to increase platelet counts. The intraretinal hemorrhages were absorbed from the area around the disc and vision recovered to 20/100 in the right eye and 20/2000 in the left after one month. Conclusion: Massive vitreoretinal hemorrhages can develop in patients with chronic refractory ITP, and vitrectomy can be beneficial for this condition.",
keywords = "Idiopatic thrombocytopenic purpura, Subretinal hemorrhage, Thrombocytopenia, Vitrectomy, Vitreous hemorrhage",
author = "Amy Okuda and Makoto Inoue and Kei Shinoda and Kazuo Tsubota",
year = "2005",
month = "11",
doi = "10.1007/s00417-005-1183-0",
language = "English",
volume = "243",
pages = "1190--1193",
journal = "Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie",
issn = "0065-6100",
publisher = "Springer Verlag",
number = "11",

}

TY - JOUR

T1 - Massive bilateral vitreoretinal hemorrhage in patient with chronic refractory idiopathic thrombocytopenic purpura

AU - Okuda, Amy

AU - Inoue, Makoto

AU - Shinoda, Kei

AU - Tsubota, Kazuo

PY - 2005/11

Y1 - 2005/11

N2 - Background: We describe a patient with chronic, refractory idiopathic thrombocytopenic purpura (ITP) who developed massive vitreoretinal hemorrhages in both eyes. Methods: A 49-year-old woman complained of an acute decrease of vision, and ophthalmoscopy revealed bilateral preretinal and subretinal hemorrhages around the optic disc. Her platelet counts were less than 5000/μl in spite of repetitive administration of corticosteroids and immunoglobulins with splenectomy for the chronic refractory ITP. One month later, she developed massive vitreoretinal hemorrhages bilaterally, and vision decreased to hand-motion. Results: Vitrectomy was performed on both eyes after medical treatment to increase platelet counts. The intraretinal hemorrhages were absorbed from the area around the disc and vision recovered to 20/100 in the right eye and 20/2000 in the left after one month. Conclusion: Massive vitreoretinal hemorrhages can develop in patients with chronic refractory ITP, and vitrectomy can be beneficial for this condition.

AB - Background: We describe a patient with chronic, refractory idiopathic thrombocytopenic purpura (ITP) who developed massive vitreoretinal hemorrhages in both eyes. Methods: A 49-year-old woman complained of an acute decrease of vision, and ophthalmoscopy revealed bilateral preretinal and subretinal hemorrhages around the optic disc. Her platelet counts were less than 5000/μl in spite of repetitive administration of corticosteroids and immunoglobulins with splenectomy for the chronic refractory ITP. One month later, she developed massive vitreoretinal hemorrhages bilaterally, and vision decreased to hand-motion. Results: Vitrectomy was performed on both eyes after medical treatment to increase platelet counts. The intraretinal hemorrhages were absorbed from the area around the disc and vision recovered to 20/100 in the right eye and 20/2000 in the left after one month. Conclusion: Massive vitreoretinal hemorrhages can develop in patients with chronic refractory ITP, and vitrectomy can be beneficial for this condition.

KW - Idiopatic thrombocytopenic purpura

KW - Subretinal hemorrhage

KW - Thrombocytopenia

KW - Vitrectomy

KW - Vitreous hemorrhage

UR - http://www.scopus.com/inward/record.url?scp=31144432892&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=31144432892&partnerID=8YFLogxK

U2 - 10.1007/s00417-005-1183-0

DO - 10.1007/s00417-005-1183-0

M3 - Article

VL - 243

SP - 1190

EP - 1193

JO - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

JF - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

SN - 0065-6100

IS - 11

ER -