Massive bilateral vitreoretinal hemorrhage in patient with chronic refractory idiopathic thrombocytopenic purpura

Amy Okuda, Makoto Inoue, Kei Shinoda, Kazuo Tsubota

Research output: Contribution to journalArticle

13 Citations (Scopus)


Background: We describe a patient with chronic, refractory idiopathic thrombocytopenic purpura (ITP) who developed massive vitreoretinal hemorrhages in both eyes. Methods: A 49-year-old woman complained of an acute decrease of vision, and ophthalmoscopy revealed bilateral preretinal and subretinal hemorrhages around the optic disc. Her platelet counts were less than 5000/μl in spite of repetitive administration of corticosteroids and immunoglobulins with splenectomy for the chronic refractory ITP. One month later, she developed massive vitreoretinal hemorrhages bilaterally, and vision decreased to hand-motion. Results: Vitrectomy was performed on both eyes after medical treatment to increase platelet counts. The intraretinal hemorrhages were absorbed from the area around the disc and vision recovered to 20/100 in the right eye and 20/2000 in the left after one month. Conclusion: Massive vitreoretinal hemorrhages can develop in patients with chronic refractory ITP, and vitrectomy can be beneficial for this condition.

Original languageEnglish
Pages (from-to)1190-1193
Number of pages4
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Issue number11
Publication statusPublished - 2005 Nov 1



  • Idiopatic thrombocytopenic purpura
  • Subretinal hemorrhage
  • Thrombocytopenia
  • Vitrectomy
  • Vitreous hemorrhage

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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