Matteuorienate A and B, two New and Potent Aldose Reductase Inhibitors from Matteuccia Orientalis (Hook.) Trev.

Shigetoshi Kadota, Purusotam Basnet, Koji Hase, Tsuneo Namba

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Matteuorienate A and B, two new C-methyl flavanone derivatives, were isolated from the Matteuccia orientalis (Hook.) Trev. (Aspidiaceae), and their structures were determined by the use of spectroscopic methods including 2D-NMR (1H-1H COSY, 1H-13C COSY and 1H-13C long-range COSY) experiments and chemical methods. Both the compounds were found to be very strong inhibitors of aldose reductase among the natural products.

Original languageEnglish
Pages (from-to)1712-1714
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume42
Issue number8
DOIs
Publication statusPublished - 1994

Keywords

  • Matteuccia orientalis
  • aldose reductase
  • matteuorienate A
  • matteuorienate B

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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