Matteuorienate A and B, two new and potent aldose reductase inhibitors from Matteuccia orientalis (Hook.) Trev.

S. Kadota, P. Basnet, Kouji Hase, T. Namba

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Matteuorienate A and B, two new C-methyl flavanone derivatives, were isolated from the Matteuccia orientalis (Hook.) Trev. (Aspidiaceae), and their structures were determined by the use of spectroscopic methods including 2D-NMR (1H-1H COSY, 1H-13C-COSY and 1H-13C long-range COSY) experiments and chemical methods. Both the compounds were found to be very strong inhibitors of aldose reductase among the natural products.

Original languageEnglish
Pages (from-to)1712-1714
Number of pages3
JournalChemical and Pharmaceutical Bulletin
Volume42
Issue number8
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

Aldehyde Reductase
Hooks
Biological Products
Nuclear magnetic resonance
Derivatives
Experiments
matteuorienate A
flavanone
matteuorienate B
Proton Magnetic Resonance Spectroscopy

Keywords

  • aldose reductase
  • Matteuccia orientalis
  • matteuorienate A
  • matteuorienate B

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

Matteuorienate A and B, two new and potent aldose reductase inhibitors from Matteuccia orientalis (Hook.) Trev. / Kadota, S.; Basnet, P.; Hase, Kouji; Namba, T.

In: Chemical and Pharmaceutical Bulletin, Vol. 42, No. 8, 1994, p. 1712-1714.

Research output: Contribution to journalArticle

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