Measurement of a stimulatory protein of RNA polymerase II in various mouse organs by the complement fixation test

Hiroomi Tamura, Kazuhisa Sekimizu, Masuo Obinata, Shunji Natori

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The amount of S-II, a protein specifically stimulating RNA polymerase II, was measured in various mouse organs by a micro complement fixation assay. The amount was almost the same in brain, liver, kidney, spleen, and Ehrlich ascites tumor cells on the basis of DNA, being about 3.8 μg/mg DNA, which corresponds to 3.6 × 105 molecules/cell. However, the amount of S-II decreased greatly during erythro-differentiation of Friend leukemia cells and no S-II was detected in matured erythrocytes.

Original languageEnglish
Pages (from-to)1475-1480
Number of pages6
JournalJournal of Biochemistry
Issue number5
Publication statusPublished - 1980 Oct
Externally publishedYes


ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Radiology Nuclear Medicine and imaging
  • Molecular Biology
  • Biochemistry

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