Measuring of optical properties of small volume samples using time-resolved reflectance spectroscopy

K. Tanaka, R. Araki, Y. Yamada, Eiji Okada

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Measurements of optical properties of biological tissues are necessary to develop optical diagnostic instruments. Although various methods to measure the optical properties of biological tissue have been proposed, very few measurements have been carried out in vivo because of their difficulties.We are developing a new method to obtain the optical properties in vivo using time -resolved measurement system. This new method determines the optical properties by comparing the experimental results of time- resolved measurement with the results of a series of Monte Carlo simulation using known optical properties. By combining results of a Monte Carlo simulation with the time-resolved reflectance measurement for the case of small source-detector distance, it is possible to measure the optical properties of small samples in vivo to which the diffusion approximation can't be applied. However, the optical properties obtained from the time-resolved reflectance method at small source-detector distances do not agree with the results from the integrating sphere system. The time- resolved reflectance at small source- detector distance should be influenced by the scattering phase function of the tissue. We discuss the effects of the phase function on the measurement of the optical properties obtained from time-resolved reflectance method.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsB. Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraka
Pages282-289
Number of pages8
Volume4250
DOIs
Publication statusPublished - 2001
EventOptical Tomography and Spectroscopy of Tissue IV - San Jose, CA, United States
Duration: 2001 Jan 212001 Jan 23

Other

OtherOptical Tomography and Spectroscopy of Tissue IV
CountryUnited States
CitySan Jose, CA
Period01/1/2101/1/23

Fingerprint

Optical properties
Spectroscopy
reflectance
optical properties
spectroscopy
Tissue
Time measurement
Detectors
detectors
time measurement
Reflectometers
Light sources
simulation
Scattering
approximation
scattering

Keywords

  • Monte Carlo simulation
  • Optical properties
  • Phase function
  • Time resolved spectroscopy

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Tanaka, K., Araki, R., Yamada, Y., & Okada, E. (2001). Measuring of optical properties of small volume samples using time-resolved reflectance spectroscopy. In B. Chance, R. R. Alfano, B. J. Tromberg, M. Tamura, & E. M. Sevick-Muraka (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4250, pp. 282-289) https://doi.org/10.1117/12.434498

Measuring of optical properties of small volume samples using time-resolved reflectance spectroscopy. / Tanaka, K.; Araki, R.; Yamada, Y.; Okada, Eiji.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / B. Chance; R.R. Alfano; B.J. Tromberg; M. Tamura; E.M. Sevick-Muraka. Vol. 4250 2001. p. 282-289.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tanaka, K, Araki, R, Yamada, Y & Okada, E 2001, Measuring of optical properties of small volume samples using time-resolved reflectance spectroscopy. in B Chance, RR Alfano, BJ Tromberg, M Tamura & EM Sevick-Muraka (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4250, pp. 282-289, Optical Tomography and Spectroscopy of Tissue IV, San Jose, CA, United States, 01/1/21. https://doi.org/10.1117/12.434498
Tanaka K, Araki R, Yamada Y, Okada E. Measuring of optical properties of small volume samples using time-resolved reflectance spectroscopy. In Chance B, Alfano RR, Tromberg BJ, Tamura M, Sevick-Muraka EM, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4250. 2001. p. 282-289 https://doi.org/10.1117/12.434498
Tanaka, K. ; Araki, R. ; Yamada, Y. ; Okada, Eiji. / Measuring of optical properties of small volume samples using time-resolved reflectance spectroscopy. Proceedings of SPIE - The International Society for Optical Engineering. editor / B. Chance ; R.R. Alfano ; B.J. Tromberg ; M. Tamura ; E.M. Sevick-Muraka. Vol. 4250 2001. pp. 282-289
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