Mechanisms of the cerebral cortical development

Kazuma Kobayashi, Kazunori Nakajima

Research output: Contribution to journalArticle

Abstract

The development of cerebral cortex is regulated by complex mechanisms. Various classes of neurons migrate from the proliferative zones to the cortex according to a spatiotemporal manner. There are two distinct modes of neuronal migration: radial migration and tangential migration. In the benefit of the advancement of research techniques such as in utero electroporation and time-lapse observation of living tissues, more aspects of the cell and molecular mechanisms that control these two migration modes and their roles in the cortical development have been clarified.

Original languageEnglish
Pages (from-to)395-403
Number of pages9
JournalBrain and Nerve
Volume60
Issue number4
Publication statusPublished - 2008 Apr

Fingerprint

Electroporation
Cerebral Cortex
Research Design
Observation
Neurons

Keywords

  • Cerebral cortex
  • Neuronal migration
  • Radial migration
  • Reelin
  • Tangential migration

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Mechanisms of the cerebral cortical development. / Kobayashi, Kazuma; Nakajima, Kazunori.

In: Brain and Nerve, Vol. 60, No. 4, 04.2008, p. 395-403.

Research output: Contribution to journalArticle

Kobayashi, K & Nakajima, K 2008, 'Mechanisms of the cerebral cortical development', Brain and Nerve, vol. 60, no. 4, pp. 395-403.
Kobayashi, Kazuma ; Nakajima, Kazunori. / Mechanisms of the cerebral cortical development. In: Brain and Nerve. 2008 ; Vol. 60, No. 4. pp. 395-403.
@article{0a970186feb1435f98cfc94a5f50b84e,
title = "Mechanisms of the cerebral cortical development",
abstract = "The development of cerebral cortex is regulated by complex mechanisms. Various classes of neurons migrate from the proliferative zones to the cortex according to a spatiotemporal manner. There are two distinct modes of neuronal migration: radial migration and tangential migration. In the benefit of the advancement of research techniques such as in utero electroporation and time-lapse observation of living tissues, more aspects of the cell and molecular mechanisms that control these two migration modes and their roles in the cortical development have been clarified.",
keywords = "Cerebral cortex, Neuronal migration, Radial migration, Reelin, Tangential migration",
author = "Kazuma Kobayashi and Kazunori Nakajima",
year = "2008",
month = "4",
language = "English",
volume = "60",
pages = "395--403",
journal = "Brain and Nerve",
issn = "0006-8969",
publisher = "Igaku-Shoin Ltd",
number = "4",

}

TY - JOUR

T1 - Mechanisms of the cerebral cortical development

AU - Kobayashi, Kazuma

AU - Nakajima, Kazunori

PY - 2008/4

Y1 - 2008/4

N2 - The development of cerebral cortex is regulated by complex mechanisms. Various classes of neurons migrate from the proliferative zones to the cortex according to a spatiotemporal manner. There are two distinct modes of neuronal migration: radial migration and tangential migration. In the benefit of the advancement of research techniques such as in utero electroporation and time-lapse observation of living tissues, more aspects of the cell and molecular mechanisms that control these two migration modes and their roles in the cortical development have been clarified.

AB - The development of cerebral cortex is regulated by complex mechanisms. Various classes of neurons migrate from the proliferative zones to the cortex according to a spatiotemporal manner. There are two distinct modes of neuronal migration: radial migration and tangential migration. In the benefit of the advancement of research techniques such as in utero electroporation and time-lapse observation of living tissues, more aspects of the cell and molecular mechanisms that control these two migration modes and their roles in the cortical development have been clarified.

KW - Cerebral cortex

KW - Neuronal migration

KW - Radial migration

KW - Reelin

KW - Tangential migration

UR - http://www.scopus.com/inward/record.url?scp=42649108704&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=42649108704&partnerID=8YFLogxK

M3 - Article

VL - 60

SP - 395

EP - 403

JO - Brain and Nerve

JF - Brain and Nerve

SN - 0006-8969

IS - 4

ER -