Mediastinal germ cell tumor with somatic-type malignancy successfully treated with chemotherapy followed by surgical resection combined with lobectomy: report of a case

Kaoru Kaseda, H. Horio, T. Hijima, T. Hatou, M. Harada

Research output: Contribution to journalArticle

Abstract

A 28-year-old male visited our hospital with complaint of chest pain. Clinical examination revealed a huge mediastinal mass which was diagnosed as non-seminomatous germ cell tumor. The patient underwent 5 cycles of chemotherapy (bleomycin, etoposide, and cisplatin) followed by resection of the tumor combined with left upper lobectomy. Final pathological diagnosis was germ cell tumor with somatic-type malignancy. While the prognosis of mediastinal germ cell tumor with somatic-type malignancy is known to be extremely poor, multimodality at an early stage is the key to successful treatment.

Original languageEnglish
Pages (from-to)1190-1193
Number of pages4
JournalKyobu geka. The Japanese journal of thoracic surgery
Volume62
Issue number13
Publication statusPublished - 2009 Dec
Externally publishedYes

Fingerprint

Germ Cell and Embryonal Neoplasms
Drug Therapy
Neoplasms
Bleomycin
Etoposide
Chest Pain
Cisplatin
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{a3684d0f86c24c55a82e1764d92e3a78,
title = "Mediastinal germ cell tumor with somatic-type malignancy successfully treated with chemotherapy followed by surgical resection combined with lobectomy: report of a case",
abstract = "A 28-year-old male visited our hospital with complaint of chest pain. Clinical examination revealed a huge mediastinal mass which was diagnosed as non-seminomatous germ cell tumor. The patient underwent 5 cycles of chemotherapy (bleomycin, etoposide, and cisplatin) followed by resection of the tumor combined with left upper lobectomy. Final pathological diagnosis was germ cell tumor with somatic-type malignancy. While the prognosis of mediastinal germ cell tumor with somatic-type malignancy is known to be extremely poor, multimodality at an early stage is the key to successful treatment.",
author = "Kaoru Kaseda and H. Horio and T. Hijima and T. Hatou and M. Harada",
year = "2009",
month = "12",
language = "English",
volume = "62",
pages = "1190--1193",
journal = "Japanese Journal of Thoracic Surgery",
issn = "0021-5252",
publisher = "Nankodo Co., Ltd.",
number = "13",

}

TY - JOUR

T1 - Mediastinal germ cell tumor with somatic-type malignancy successfully treated with chemotherapy followed by surgical resection combined with lobectomy

T2 - report of a case

AU - Kaseda, Kaoru

AU - Horio, H.

AU - Hijima, T.

AU - Hatou, T.

AU - Harada, M.

PY - 2009/12

Y1 - 2009/12

N2 - A 28-year-old male visited our hospital with complaint of chest pain. Clinical examination revealed a huge mediastinal mass which was diagnosed as non-seminomatous germ cell tumor. The patient underwent 5 cycles of chemotherapy (bleomycin, etoposide, and cisplatin) followed by resection of the tumor combined with left upper lobectomy. Final pathological diagnosis was germ cell tumor with somatic-type malignancy. While the prognosis of mediastinal germ cell tumor with somatic-type malignancy is known to be extremely poor, multimodality at an early stage is the key to successful treatment.

AB - A 28-year-old male visited our hospital with complaint of chest pain. Clinical examination revealed a huge mediastinal mass which was diagnosed as non-seminomatous germ cell tumor. The patient underwent 5 cycles of chemotherapy (bleomycin, etoposide, and cisplatin) followed by resection of the tumor combined with left upper lobectomy. Final pathological diagnosis was germ cell tumor with somatic-type malignancy. While the prognosis of mediastinal germ cell tumor with somatic-type malignancy is known to be extremely poor, multimodality at an early stage is the key to successful treatment.

UR - http://www.scopus.com/inward/record.url?scp=74249100234&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74249100234&partnerID=8YFLogxK

M3 - Article

C2 - 19999102

AN - SCOPUS:74249100234

VL - 62

SP - 1190

EP - 1193

JO - Japanese Journal of Thoracic Surgery

JF - Japanese Journal of Thoracic Surgery

SN - 0021-5252

IS - 13

ER -