Medications and fall risk: a case–control study in nursing home residents in Japan

Hyerim Park, Hiroki Satoh, Akiko Miki, Hideyuki Maki, Kohei Asai, Akira Shiraishi, Hisashi Urushihara, Yasufumi Sawada

Research output: Contribution to journalArticle

Abstract

Aim: Falls are a significant problem for older people, but are few studies of the risk of falling in residents of nursing homes in Japan. We aimed to investigate the risk factors for falls and the association of medication use and falls in nursing home residents in Japan. Methods: This case–control study reviewed the records of residents of who were ≥ 65 years of age and had fallen in 2012 and an age-, sex-, and facility-matched control group selected from 58 nursing homes in Japan. The odds ratios of potential risk factors and current medications were determined by conditional logistic regression. Results: A total of 1832 residents (916 cases and 916 controls) were included. Falls were significantly associated with an inability to walk without assistance or stand up without assistance, need for toileting assistance, visual impairment, insomnia, and dementia. Current prescription of antithrombotic, nonsteroidal anti-inflammatory, or antiparkinson drugs, muscle relaxants, antiepileptics, antipsychotics, antidepressants, opioids, selective serotonin reuptake inhibitors, and memantine was also associated with increased risk of falling. Conclusions: Many medications were associated with falls in nursing homes residents in Japan. To prevent these falls, caregivers should provide adequate care, and healthcare professionals should consider switching or dose reduction for these medications.

Original languageEnglish
JournalAging Clinical and Experimental Research
DOIs
Publication statusPublished - 2019 Jan 1

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Nursing Homes
Japan
Accidental Falls
Facility Regulation and Control
Memantine
Antiparkinson Agents
Vision Disorders
Serotonin Uptake Inhibitors
Sleep Initiation and Maintenance Disorders
Anticonvulsants
Opioid Analgesics
Antidepressive Agents
Caregivers
Antipsychotic Agents
Prescriptions
Dementia
Anti-Inflammatory Agents
Research Design
Logistic Models
Odds Ratio

Keywords

  • Accidental falls
  • Comorbidity
  • Nursing home
  • Prescription drugs
  • Risk factors

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

Medications and fall risk : a case–control study in nursing home residents in Japan. / Park, Hyerim; Satoh, Hiroki; Miki, Akiko; Maki, Hideyuki; Asai, Kohei; Shiraishi, Akira; Urushihara, Hisashi; Sawada, Yasufumi.

In: Aging Clinical and Experimental Research, 01.01.2019.

Research output: Contribution to journalArticle

Park, Hyerim ; Satoh, Hiroki ; Miki, Akiko ; Maki, Hideyuki ; Asai, Kohei ; Shiraishi, Akira ; Urushihara, Hisashi ; Sawada, Yasufumi. / Medications and fall risk : a case–control study in nursing home residents in Japan. In: Aging Clinical and Experimental Research. 2019.
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