Meta-analysis of laparoscopic surgery for recurrent Crohn’s disease

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5 Citations (Scopus)

Abstract

Purposes: It remains unclear whether laparoscopic surgery is suitable for recurrent Crohn’s disease (CD). The objective of this meta-analysis was to evaluate the safety and feasibility of laparoscopic resection for recurrent vs. primary CD by comparing intraoperative and postoperative outcomes. Methods: We searched the PubMed and Cochrane Library databases for studies that compared complications associated with laparoscopic resection for primary and recurrent CD. The primary study endpoints were conversion rates and postoperative complication rates. Results: Seven trials with a collective total of 627 participants (413 with primary CD and 214 with recurrent CD) met our inclusion criteria. Laparoscopic resection was associated with a significantly higher conversion rate when performed for recurrent CD than for primary CD (OR = 2.53; 95 % CI 1.22–5.25; p = 0.01). However, there was no significant difference in the total complication rate between laparoscopic resection for primary vs. that for recurrent CD (OR = 1.41; 95 % CI 0.86–2.34; p = 0.18). Conclusions: Although a higher conversion rate suggests technical complexity, laparoscopic resection for recurrent CD is considered a safe and feasible procedure, without an increased risk of postoperative complications.

Original languageEnglish
JournalSurgery Today
DOIs
Publication statusAccepted/In press - 2015 Nov 3

Fingerprint

Crohn Disease
Laparoscopy
Meta-Analysis
PubMed
Libraries
Databases
Safety

Keywords

  • Crohn’s disease
  • Laparoscopic surgery
  • Meta-analysis
  • Recurrent

ASJC Scopus subject areas

  • Surgery

Cite this

@article{d63a1357eb194a779600fe15d6e989f5,
title = "Meta-analysis of laparoscopic surgery for recurrent Crohn’s disease",
abstract = "Purposes: It remains unclear whether laparoscopic surgery is suitable for recurrent Crohn’s disease (CD). The objective of this meta-analysis was to evaluate the safety and feasibility of laparoscopic resection for recurrent vs. primary CD by comparing intraoperative and postoperative outcomes. Methods: We searched the PubMed and Cochrane Library databases for studies that compared complications associated with laparoscopic resection for primary and recurrent CD. The primary study endpoints were conversion rates and postoperative complication rates. Results: Seven trials with a collective total of 627 participants (413 with primary CD and 214 with recurrent CD) met our inclusion criteria. Laparoscopic resection was associated with a significantly higher conversion rate when performed for recurrent CD than for primary CD (OR = 2.53; 95 {\%} CI 1.22–5.25; p = 0.01). However, there was no significant difference in the total complication rate between laparoscopic resection for primary vs. that for recurrent CD (OR = 1.41; 95 {\%} CI 0.86–2.34; p = 0.18). Conclusions: Although a higher conversion rate suggests technical complexity, laparoscopic resection for recurrent CD is considered a safe and feasible procedure, without an increased risk of postoperative complications.",
keywords = "Crohn’s disease, Laparoscopic surgery, Meta-analysis, Recurrent",
author = "Kohei Shigeta and Koji Okabayashi and Hirotoshi Hasegawa and Masashi Tsuruta and Ryo Seishima and Yuukou Kitagawa",
year = "2015",
month = "11",
day = "3",
doi = "10.1007/s00595-015-1271-7",
language = "English",
journal = "Surgery Today",
issn = "0941-1291",
publisher = "Springer Japan",

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T1 - Meta-analysis of laparoscopic surgery for recurrent Crohn’s disease

AU - Shigeta, Kohei

AU - Okabayashi, Koji

AU - Hasegawa, Hirotoshi

AU - Tsuruta, Masashi

AU - Seishima, Ryo

AU - Kitagawa, Yuukou

PY - 2015/11/3

Y1 - 2015/11/3

N2 - Purposes: It remains unclear whether laparoscopic surgery is suitable for recurrent Crohn’s disease (CD). The objective of this meta-analysis was to evaluate the safety and feasibility of laparoscopic resection for recurrent vs. primary CD by comparing intraoperative and postoperative outcomes. Methods: We searched the PubMed and Cochrane Library databases for studies that compared complications associated with laparoscopic resection for primary and recurrent CD. The primary study endpoints were conversion rates and postoperative complication rates. Results: Seven trials with a collective total of 627 participants (413 with primary CD and 214 with recurrent CD) met our inclusion criteria. Laparoscopic resection was associated with a significantly higher conversion rate when performed for recurrent CD than for primary CD (OR = 2.53; 95 % CI 1.22–5.25; p = 0.01). However, there was no significant difference in the total complication rate between laparoscopic resection for primary vs. that for recurrent CD (OR = 1.41; 95 % CI 0.86–2.34; p = 0.18). Conclusions: Although a higher conversion rate suggests technical complexity, laparoscopic resection for recurrent CD is considered a safe and feasible procedure, without an increased risk of postoperative complications.

AB - Purposes: It remains unclear whether laparoscopic surgery is suitable for recurrent Crohn’s disease (CD). The objective of this meta-analysis was to evaluate the safety and feasibility of laparoscopic resection for recurrent vs. primary CD by comparing intraoperative and postoperative outcomes. Methods: We searched the PubMed and Cochrane Library databases for studies that compared complications associated with laparoscopic resection for primary and recurrent CD. The primary study endpoints were conversion rates and postoperative complication rates. Results: Seven trials with a collective total of 627 participants (413 with primary CD and 214 with recurrent CD) met our inclusion criteria. Laparoscopic resection was associated with a significantly higher conversion rate when performed for recurrent CD than for primary CD (OR = 2.53; 95 % CI 1.22–5.25; p = 0.01). However, there was no significant difference in the total complication rate between laparoscopic resection for primary vs. that for recurrent CD (OR = 1.41; 95 % CI 0.86–2.34; p = 0.18). Conclusions: Although a higher conversion rate suggests technical complexity, laparoscopic resection for recurrent CD is considered a safe and feasible procedure, without an increased risk of postoperative complications.

KW - Crohn’s disease

KW - Laparoscopic surgery

KW - Meta-analysis

KW - Recurrent

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